Maximizing the oil content in polysaccharide-based emulsion gels for the development of tissue mimicking phantoms
Artikel i vetenskaplig tidskrift, 2021

Formulations based on agar and κ-carrageenan were investigated for the production of emulsion gels applicable as tissue mimicking phantoms. The effects of the polysaccharide matrix, the oil content and the presence of surfactants on the micro-/nanostructure, rheology, and mechanical and dielectric properties were investigated. Results showed a high capacity of the agar to stabilize oil droplets, producing gels with smaller (10−21 μm) and more uniform oil droplets. The addition of surfactants allowed increasing the oil content and reduced the gel strength and stiffness down to 57 % and 34 %, respectively. The permittivity and conductivity of the gels were reduced by increasing the oil content, especially in the agar gels (18.8 and 0.05 S/m, respectively), producing materials with dielectric properties similar to those of low-water content tissues. These results evidence the suitability of these polysaccharides to design a variety of tissue mimicking phantoms with a broad range of mechanical and dielectric properties.

X-ray scattering

Gelation

Surfactant

Seaweed polysaccharides

Tissue mimicking

Författare

Cynthia Fontes-Candia

Consejo Superior de Investigaciones Científicas (CSIC)

Patricia Lopez-Sanchez

RISE Research Institutes of Sweden

Anna Ström

Chalmers, Kemi och kemiteknik, Tillämpad kemi

Juan Carlos Martínez

El Sincrotrón ALBA

Ana Salvador

Consejo Superior de Investigaciones Científicas (CSIC)

Teresa Sanz

Consejo Superior de Investigaciones Científicas (CSIC)

Hana Dobsicek Trefna

Chalmers, Elektroteknik, Signalbehandling och medicinsk teknik

Amparo López-Rubio

Consejo Superior de Investigaciones Científicas (CSIC)

Marta Martínez-Sanz

Consejo Superior de Investigaciones Científicas (CSIC)

Carbohydrate Polymers

0144-8617 (ISSN)

Vol. 256 117496

Ämneskategorier (SSIF 2011)

Polymerkemi

Livsmedelsteknik

Polymerteknologi

DOI

10.1016/j.carbpol.2020.117496

PubMed

33483023

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Senast uppdaterat

2025-03-09