Precision nutrition for cardiometabolic diseases
Reviewartikel, 2025
Precision nutrition is a vibrant and rapidly evolving field of scientific research and innovation with the potential to deliver health, societal and economic benefits by improving healthcare delivery and policies. Advances in deep phenotyping technologies, digital tools and artificial intelligence have made possible early proof-of-concept research that expands the understanding of within- and between-person variability in responses to diet. These studies illustrate the promise of precision nutrition to complement the traditional ‘one size fits all’ dietary guidelines, which, while considering broad life-stage and disease-specific nutritional requirements, often lack the granularity to account fully for individual variations in nutritional needs and dietary responses. Despite these developments, however, considerable challenges remain before precision nutrition can be implemented on a broader scale. This Review examines the current state of precision nutrition research, with a focus on its application to reducing the incidence and burden of cardiometabolic diseases. We critically examine the evidence base, explore the potential benefits and discuss the challenges and opportunities ahead.
Författare
Marta Guasch-Ferré
Harvard School of Public Health
Novo Nordisk Fonden
Köpenhamns universitet
Clemens Wittenbecher
Chalmers, Life sciences, Livsmedelsvetenskap
Marie Palmnäs
Chalmers, Life sciences, Livsmedelsvetenskap
Orly Ben-Yacov
Weizmann Institute of Science
Ellen E. Blaak
Universiteit Maastricht
Christina C. Dahm
Aarhus Universitet
Tove Fall
Uppsala universitet
Berit L. Heitmann
Faculty of Medicine and Health
Frederiksberg Hospital
Köpenhamns universitet
Tine Rask Licht
Danmarks Tekniske Universitet (DTU)
M. Lof
Karolinska Institutet
Linköpings universitet
Ruth Loos
Novo Nordisk Fonden
Chirag J. Patel
Harvard Medical School
Carmelo Quarta
Université de Bordeaux
Leanne M. Redman
Pennington Biomedical Research Center
Eran Segal
Weizmann Institute of Science
Nicola Segata
Universita degli Studi di Trento
Istituto Europeo di Oncologia
Michael P. Snyder
Stanford University
Qi Sun
Harvard School of Public Health
Brigham and Women's Hospital
Deirdre K. Tobias
Brigham and Women's Hospital
Harvard School of Public Health
Frank B. Hu
Brigham and Women's Hospital
Harvard School of Public Health
Paul W. Franks
Lunds universitet
University of Oxford
Harvard School of Public Health
Rikard Landberg
Chalmers, Life sciences, Livsmedelsvetenskap
Jennifer L. Sargent
BabelFisk
Department of Metabolism
Jordi Merino
Massachusetts General Hospital
Novo Nordisk Fonden
Broad Institute
Nature Medicine
1078-8956 (ISSN) 1546170x (eISSN)
Vol. In PressFingeravtryck i metabolomet från en kontrollerad modifiering av kolhydratkvalitet i kosten belyser långsiktig påverkan på kardiometabol sjukdomsrisk och ger nya verktyg för precisionsprevention
Vetenskapsrådet (VR) (2022-01529), 2023-01-01 -- 2026-12-31.
Ämneskategorier (SSIF 2025)
Näringslära och dietkunskap
DOI
10.1038/s41591-025-03669-9
PubMed
40307513