Precision nutrition for cardiometabolic diseases
Reviewartikel, 2025

Precision nutrition is a vibrant and rapidly evolving field of scientific research and innovation with the potential to deliver health, societal and economic benefits by improving healthcare delivery and policies. Advances in deep phenotyping technologies, digital tools and artificial intelligence have made possible early proof-of-concept research that expands the understanding of within- and between-person variability in responses to diet. These studies illustrate the promise of precision nutrition to complement the traditional ‘one size fits all’ dietary guidelines, which, while considering broad life-stage and disease-specific nutritional requirements, often lack the granularity to account fully for individual variations in nutritional needs and dietary responses. Despite these developments, however, considerable challenges remain before precision nutrition can be implemented on a broader scale. This Review examines the current state of precision nutrition research, with a focus on its application to reducing the incidence and burden of cardiometabolic diseases. We critically examine the evidence base, explore the potential benefits and discuss the challenges and opportunities ahead.

Författare

Marta Guasch-Ferré

Köpenhamns universitet

Harvard School of Public Health

Novo Nordisk Fonden

Clemens Wittenbecher

Chalmers, Life sciences, Livsmedelsvetenskap

Marie Palmnäs

Chalmers, Life sciences, Livsmedelsvetenskap

Orly Ben-Yacov

Weizmann Institute of Science

Ellen E. Blaak

Universiteit Maastricht

Christina C. Dahm

Aarhus Universitet

Tove Fall

Uppsala universitet

Berit L. Heitmann

Köpenhamns universitet

Faculty of Medicine and Health

Frederiksberg Hospital

Tine Rask Licht

Danmarks Tekniske Universitet (DTU)

M. Lof

Linköpings universitet

Karolinska Institutet

Ruth Loos

Novo Nordisk Fonden

Chirag J. Patel

Harvard Medical School

Carmelo Quarta

Université de Bordeaux

Leanne M. Redman

Pennington Biomedical Research Center

Eran Segal

Weizmann Institute of Science

Nicola Segata

Universita degli Studi di Trento

Istituto Europeo di Oncologia

Michael P. Snyder

Stanford University

Qi Sun

Harvard School of Public Health

Brigham and Women's Hospital

Deirdre K. Tobias

Harvard School of Public Health

Brigham and Women's Hospital

Frank B. Hu

Harvard School of Public Health

Brigham and Women's Hospital

Paul W. Franks

University of Oxford

Lunds universitet

Harvard School of Public Health

Rikard Landberg

Chalmers, Life sciences, Livsmedelsvetenskap

Jennifer L. Sargent

Department of Metabolism

BabelFisk

Jordi Merino

Novo Nordisk Fonden

Broad Institute

Massachusetts General Hospital

Nature Medicine

1078-8956 (ISSN) 1546170x (eISSN)

Vol. In Press

Fingeravtryck i metabolomet från en kontrollerad modifiering av kolhydratkvalitet i kosten belyser långsiktig påverkan på kardiometabol sjukdomsrisk och ger nya verktyg för precisionsprevention

Vetenskapsrådet (VR) (2022-01529), 2023-01-01 -- 2026-12-31.

Ämneskategorier (SSIF 2025)

Näringslära och dietkunskap

DOI

10.1038/s41591-025-03669-9

Mer information

Senast uppdaterat

2025-05-09