Finding at-DNA--kinetic recognition of long adenine-thymine stretches by metal-ligand complexes.

Artikel i vetenskaplig tidskrift, 2008

High selectivity for long AT sequences can be attained by kinetically controlled DNA threading intercalation by binuclear ruthenium(II) complexes. The rate of intercalation is strongly correlated to the number of consecutive AT basepairs, being up to 2500 times faster with an AT polymer compared to mixed-sequence DNA.