Anastasia Krivoruchko

Gästforskare at Systems and Synthetic Biology

Dr. Anastasia Krivoruchko is a project leader in the Systems and Synthetic Biology Group. Her research is focused on using metabolic engineering to create yeast cell factories for production of compounds of interest. This includes yeast cells able to produce 1-butanol, a potentially important biofuel. Another project involves the creation of platform yeast cell factories containing enriched levels of cytosolic acetyl-CoA, a precursor molecule for various biotech products.

Source: chalmers.se

Showing 16 publications

2019

Engineering yeast phospholipid metabolism for de novo oleoylethanolamide production

Yi Liu, Quanli Liu, Anastasia Krivoruchko et al
Nature Chemical Biology. Vol. In Press
Journal article
2018

Screening of 2A peptides for polycistronic gene expression in yeast

Tatiana M. Souza-Moreira, Clara Navarrete Roman, Xin Chen et al
FEMS Yeast Research. Vol. 18 (5)
Journal article
2017

Expanding the product portfolio of fungal type I fatty acid synthases

Zhu Zhiwei, Yongjin Zhou, Anastasia Krivoruchko et al
Nature Chemical Biology. Vol. 13 (4), p. 360-362
Journal article
2017

Enabling the synthesis of medium chain alkanes and 1-alkenes in yeast

Zhu Zhiwei, Yongjin Zhou, Min-Kyoung Kang et al
Metabolic Engineering. Vol. 44 (NOV), p. 81-88
Journal article
2017

Metabolic engineering of Saccharomyces cerevisiae for production of very long chain fatty acid-derived chemicals

Tao Yu, Yongjin Zhou, Leonie Wenning et al
Nature Communications. Vol. 8, p. Article number: 15587-
Journal article
2017

Metabolic engineering of Saccharomyces cerevisiae for production of germacrene A, a precursor of beta-elemene

Yating Hu, Yongjin Zhou, Jichen Bao et al
Journal of Industrial Microbiology and Biotechnology. Vol. 44 (7), p. 1065-1072
Journal article
2016

Industrial systems biology and its impact on synthetic biology of yeast cell factories

Eugene Fletcher, Anastasia Krivoruchko, Jens B Nielsen
Biotechnology and Bioengineering. Vol. 113 (6), p. 1164-1170
Journal article
2015

Functional pyruvate formate lyase pathway expressed with two different electron donors in Saccharomyces cerevisiae at aerobic growth

Yiming Zhang, Zongijie Dai, Anastasia Krivoruchko et al
FEMS Yeast Research. Vol. 15 (4)
Journal article
2015

Microbial acetyl-CoA metabolism and metabolic engineering

Anastasia Krivoruchko, Yiming Zhang, Verena Siewers et al
Metabolic Engineering. Vol. 28, p. 28-42
Journal article
2015

Modular pathway rewiring of Saccharomyces cerevisiae enables high-level production of L-ornithine

J. Qin, Yongjin Zhou, Anastasia Krivoruchko et al
Nature Communications. Vol. 6 (Sept.), p. Art. no. 8224-
Journal article
2015

Adaptive mutations in sugar metabolism restore growth on glucose in a pyruvate decarboxylase negative yeast strain

Yiming Zhang, Guodong Liu, Martin Engqvist et al
Microbial Cell Factories. Vol. 14 (116)
Journal article
2015

Production of natural products through metabolic engineering of Saccharomyces cerevisiae

Anastasia Krivoruchko, Jens B Nielsen
Current Opinion in Biotechnology. Vol. 35, p. 7-15
Journal article
2014

Activation of the carbohydrate response element binding protein (ChRESP) in response to anoxia in the turtle Trachemys scripta elegans

Anastasia Krivoruchko, K. B. Storey
Biochimica et Biophysica Acta - General Subjects. Vol. 1840 (10), p. 3000-3005
Journal article
2013

Activation of the unfolded protein response during anoxia exposure in the turtle Trachemys scripta elegans

Anastasia Krivoruchko, K.B. Storey
Molecular and Cellular Biochemistry. Vol. 374 (1-2), p. 91-103
Journal article
2013

Improving biobutanol production in engineered Saccharomyces cerevisiae by manipulation of acetyl-CoA metabolism

Anastasia Krivoruchko, Cristina Serrano-Amatriain, Yun Chen et al
Journal of Industrial Microbiology and Biotechnology. Vol. 40 (9), p. 1051-1056
Journal article
2011

Opportunities for yeast metabolic engineering: Lessons from synthetic biology

Verena Siewers, Jens B Nielsen, Anastasia Krivoruchko
Biotechnology journal. Vol. 6 (3), p. 262-276
Journal article

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