Tailormade Polysaccharides with Defined Branching Patterns: Enzymatic Polymerization of Arabinoxylan Oligosaccharides
Artikel i vetenskaplig tidskrift, 2018

The heterogeneous nature of non-cellulosic polysaccharides, such as arabinoxylan, makes it difficult to correlate molecular structure with macroscopic properties. To study the impact of specific structural features of the polysaccharides on crystallinity or affinity to other cell wall components, collections of polysaccharides with defined repeating units are required. Herein, a chemoenzymatic approach to artificial arabinoxylan polysaccharides with systematically altered branching patterns is described. The polysaccharides were obtained by glycosynthase-catalyzed polymerization of glycosyl fluorides derived from arabinoxylan oligosaccharides. X-ray diffraction and adsorption experiments on cellulosic surfaces revealed that the physicochemical properties of the synthetic polysaccharides strongly depend on the specific nature of their substitution patterns. The artificial polysaccharides allow structure–property relationship studies that are not accessible by other means.

synthetic methods

enzymes

carbohydrates

glycosynthases

structure elucidation

Författare

Deborah Senf

Freie Universität Berlin

Max Planck-institutet

Colin Ruprecht

Max Planck-institutet

Saina Kishani

Kungliga Tekniska Högskolan (KTH)

Aleksandar Matic

Universität Potsdam

Max Planck-institutet

Guillermo Toriz Gonzalez

Chalmers, Kemi och kemiteknik, Tillämpad kemi, Polymerteknologi

Paul Gatenholm

Paul Gatenholm Group

L. Wagberg

Kungliga Tekniska Högskolan (KTH)

Fabian Pfrengle

Freie Universität Berlin

Max Planck-institutet

Angewandte Chemie - International Edition

1433-7851 (ISSN) 1521-3773 (eISSN)

Vol. 57 37 11987-11992

Ämneskategorier

Textil-, gummi- och polymermaterial

Annan kemi

Organisk kemi

DOI

10.1002/anie.201806871

Mer information

Senast uppdaterat

2018-09-13