Morten Grötli

2023

Fluorescent Molecular Photoswitches for the Generation of All-Optical Encryption Keys

2022

Design and development of photoswitchable DFG-Out RET kinase inhibitors

2020

Peroxiredoxin promotes longevity and H2O2-resistance in yeast through redox-modulation of protein kinase A

2020

Lighting Up DNA with the Environment-Sensitive Bright Adenine Analogue qAN4

2020

Getting DNA and RNA out of the dark with 2CNqA: a bright adenine analogue and interbase FRET donor

2020

A Redox-Sensitive Thiol in Wis1 Modulates the Fission Yeast Mitogen-Activated Protein Kinase Response to H2O2 and Is the Target of a Small Molecule

2019

A Fluorescent Kinase Inhibitor that Exhibits Diagnostic Changes in Emission upon Binding

2019

Interbase FRET in RNA: from A to Z

2018

Pulse-shaped two-photon excitation of a fluorescent base analogue approaches single-molecule sensitivity

2018

Synthesis and Photophysical Characterization of Azoheteroarenes

2018

Synthesis, oligonucleotide incorporation and fluorescence properties in DNA of a bicyclic thymine analogue

2018

Shining New Light on the Spiropyran Photoswitch: A Photocage Decides between cis-trans or Spiro-Merocyanine Isomerization

2018

Drug Repositioning for Effective Prostate Cancer Treatment

2018

Pentacyclic adenine: A versatile and exceptionally bright fluorescent DNA base analogue

2017

Fluorescent nucleobase analogues for base-base FRET in nucleic acids: Synthesis, photophysics and applications

2017

On the use of diarylmaleimide derivatives in biological contexts: An investigation of the photochromic properties in aqueous solution

Improving the economics of NASH/NAFLD treatment through the use of systems biology

2017

Toward Complete Sequence Flexibility of Nucleic Acid Base Analogue FRET

2017

Network analyses identify liver-specific targets for treating liver diseases

2016

An acido- and photochromic molecular device that mimics triode action

7-(Benzofuran-2-yl)-7-deazadeoxyguanosine as a fluorescence turn-ON probe for single-strand DNA binding protein

Structural Insights into the Polyphyletic Origins of Glycyl tRNA Synthetases

2015

Second-Generation Fluorescent Quadracyclic Adenine Analogues: Environment-Responsive Probes with Enhanced Brightness

Design, Synthesis and Evaluation of 2,5-Diketopiperazines as Inhibitors of the MDM2-p53 Interaction

2015

8-Triazolylpurines: Towards Fluorescent Inhibitors of the MDM2/p53 Interaction

2015

Development of bright fluorescent quadracyclic adenine analogues: TDDFT-calculation supported rational design

2015

Design, Synthesis and Inhibitory Activity of Photoswitchable RET Kinase Inhibitors.

2015

A Caged Ret Kinase Inhibitor and its Effect on Motoneuron Development in Zebrafish Embryos

Application of a peptide-based assay to characterize inhibitors targeting protein kinases from yeast

Synthesis and photophysical characterisation of new fluorescent triazole adenine analogues

2014

Inhibition of MAPK Hog1 Results in Increased Hsp104 Aggregate Formation Probably through Elevated Arsenite Influx into the Cells, an Approach with Numerous Potential Applications

2014

A Single-Cell Study of a Highly Effective Hog1 Inhibitor for in Situ Yeast Cell Manipulation

Photoswitch kinase inhibitors

Effect of MAPK Inhibitor on the Arsenite uptake by Aquaglyceroporin in Single Yeast Cells.

Synthesis and photophysical characterization of 1-and 4-(purinyl) triazoles

Determination of primary sequence specificity of Arabidopsis MAPKs MPK3 and MPK6 leads to identification of new substrates.

2012

Design and evaluation of a microfluidic system for inhibition studies of yeast cell signaling

Solid-Phase Synthesis of 5 '-O- N-(Acyl)sulfamoyl adenosine Derivatives

Design, synthesis, and characterization of a highly effective Hog1 inhibitor: a powerful tool for analyzing MAP kinase signaling in yeast.

2011

Characterization of photophysical and base-mimicking properties of a novel fluorescent adenine analogue in DNA

Design, synthesis and characterization of a highly effective Hog1 inhibitor: a powerful tool for analyzing MAP kinase signalling in yeast

Design, synthesis and characterization of a highly effective Hog1 inhibitor: a powerful tool for analyzing MAP kinase signalling in yeast

Positional Scanning Peptide Libraries for Kinase Substrate Specificity Determinations: Straightforward and Reproducible Synthesis Using Pentafluorophenyl Esters.

2,6,8-Trisubstituted 3-hydroxychromone derivatives as fluorophores for live-cell imaging.

Short cut to 1,2,3-triazole-based p38 MAP kinase inhibitors via [3+2]-cycloaddition chemistry

Highly selective, cell-permeable and fast-acting wild-type Hog1 inhibitors as tools for studying cellular function of kinases

Synthesis and use of positional scanning peptide libraries for determination of kinase substrate consensus sequences

Synthesis and Photophysical Characterisation of Fluorescent 8-(1H-1,2,3-Triazol-4-yl)adenosine Derivatives

Specificity of MAP kinase substrates – determination of consensus sequences using positional scanning peptide libraries