Morten Grötli

Full Professor at University of Gothenburg, Department of Chemistry

Showing 41 publications

2018

Drug Repositioning for Effective Prostate Cancer Treatment

Beste Turanli, Morten Grötli, Jan Boren et al
Frontiers in Physiology. Vol. 9
Journal article
2018

Pentacyclic adenine: A versatile and exceptionally bright fluorescent DNA base analogue

Mattias Bood, Anders Foller Füchtbauer, Moa Sandberg Wranne et al
Chemical Science. Vol. 9 (14), p. 3494-3502
Journal article
2018

Shining New Light on the Spiropyran Photoswitch: A Photocage Decides between cis-trans or Spiro-Merocyanine Isomerization

Cassandra Fleming, Shiming Li, Morten Grötli et al
Journal of the American Chemical Society. Vol. 140, p. 14069-14072
Journal article
2018

Synthesis, oligonucleotide incorporation and fluorescence properties in DNA of a bicyclic thymine analogue

Christopher Lawson, Anders Foller Füchtbauer, Moa Sandberg Wranne et al
Scientific Reports. Vol. 8 (1)
Journal article
2018

Pulse-shaped two-photon excitation of a fluorescent base analogue approaches single-molecule sensitivity

Rachel S. Fisher, David Nobis, Anders Foller Füchtbauer et al
Physical Chemistry Chemical Physics. Vol. 20 (45), p. 28487-28498
Journal article
2018

Synthesis and Photophysical Characterization of Azoheteroarenes

Yongjin Xu, Chunxia Gao, Joakim Andreasson et al
Organic Letters. Vol. 20 (16), p. 4875-4879
Journal article
2017

Fluorescent nucleobase analogues for base-base FRET in nucleic acids: Synthesis, photophysics and applications

Mattias Bood, Sangamesh Sarangamath, Moa Sandberg Wranne et al
Beilstein Journal of Organic Chemistry. Vol. 14, p. 114-129
Review article
2017

On the use of diarylmaleimide derivatives in biological contexts: An investigation of the photochromic properties in aqueous solution

Cassandra Fleming, Patricia Remón Ruiz, Shiming Li et al
Dyes and Pigments. Vol. 137, p. 410-420
Journal article
2017

Toward Complete Sequence Flexibility of Nucleic Acid Base Analogue FRET

Moa Sandberg Wranne, Anders Foller Füchtbauer, Blaise Dumat et al
Journal of the American Chemical Society. Vol. 139 (27), p. 9271-9280
Journal article
2017

Network analyses identify liver-specific targets for treating liver diseases

SangWook Lee, C. Zhang, Z. T. Liu et al
Molecular Systems Biology. Vol. 13 (8)
Journal article
2017

Improving the economics of NASH/NAFLD treatment through the use of systems biology

J. Bosley, C. Boren, SangWook Lee et al
Drug Discovery Today. Vol. 22 (10), p. 1532-1538
Journal article
2016

An acido- and photochromic molecular device that mimics triode action

Patricia Remón Ruiz, Shiming Li, Morten Grötli et al
Chemical Communications. Vol. 52 (25), p. 4659-4662
Journal article
2016

Structural Insights into the Polyphyletic Origins of Glycyl tRNA Synthetases

M. I. Valencia-Sanchez, A. Rodriguez-Hernandez, Ruben Ferreira et al
Journal of Biological Chemistry. Vol. 291 (28), p. 14430-14446
Journal article
2016

7-(Benzofuran-2-yl)-7-deazadeoxyguanosine as a fluorescence turn-ON probe for single-strand DNA binding protein

M. Tokugawa, Y. Masaki, J. C. Canggadibrata et al
Chemical Communications. Vol. 52 (19), p. 3809-3812
Journal article
2015

Design, Synthesis and Inhibitory Activity of Photoswitchable RET Kinase Inhibitors.

Ruben Ferreira, Jesper Nilsson, Carlos Solano et al
Scientific Reports. Vol. 5, p. artikel nr 9769-
Journal article
2015

A Caged Ret Kinase Inhibitor and its Effect on Motoneuron Development in Zebrafish Embryos

David Bliman, Jesper Nilsson, Petronella Kettunen et al
Scientific Reports. Vol. 5, p. artikel nr 13109-
Journal article
2015

Development of bright fluorescent quadracyclic adenine analogues: TDDFT-calculation supported rational design

Anders Foller Füchtbauer, Blaise Dumat, Moa Sandberg Wranne et al
Scientific Reports. Vol. 5, p. art. no. 12653-
Journal article
2015

Design, Synthesis and Evaluation of 2,5-Diketopiperazines as Inhibitors of the MDM2-p53 Interaction

Mariell Pettersson, Maria Quant, J. Min et al
PLoS ONE. Vol. 10 (10)
Journal article
2015

8-Triazolylpurines: Towards Fluorescent Inhibitors of the MDM2/p53 Interaction

Mariell Pettersson, David Bliman, Jimmy Jacobsson et al
PLoS ONE. Vol. 10 (5), p. e0124423-
Journal article
2015

Second-Generation Fluorescent Quadracyclic Adenine Analogues: Environment-Responsive Probes with Enhanced Brightness

Blaise Dumat, Mattias Bood, Moa Sandberg Wranne et al
Chemistry - A European Journal. Vol. 21 (10), p. 4039-4048
Journal article
2014

Synthesis and photophysical characterisation of new fluorescent triazole adenine analogues

Christopher Lawson, Anke Dierckx, Francois-Alexandre Miannay et al
Organic and Biomolecular Chemistry. Vol. 12 (28), p. 5158-5167
Journal article
2014

Application of a peptide-based assay to characterize inhibitors targeting protein kinases from yeast

Jenny Veide Vilg, S. Dahal, T. Ljungdahl et al
Current Genetics. Vol. 60 (3), p. 193-200
Journal article
2014

Inhibition of MAPK Hog1 Results in Increased Hsp104 Aggregate Formation Probably through Elevated Arsenite Influx into the Cells, an Approach with Numerous Potential Applications

Doryaneh Ahmadpour, Amin Abbaszadehbanaeiyan, Morten Grötli et al
American Journal of Molecular Biology. Vol. 4 (2), p. 59-71
Journal article
2014

A Single-Cell Study of a Highly Effective Hog1 Inhibitor for in Situ Yeast Cell Manipulation

Charlotte Hamngren Blomqvist, Peter Dinér, Morten Grötli et al
Micromachines. Vol. 5 (1), p. 81-96
Journal article
2014

Photoswitch kinase inhibitors

Raphael Ferreira, Jesper Nilsson, C. Solano et al
Purinergic Signalling. Vol. 10 (4), p. 767-768
Magazine article
2013

Synthesis and photophysical characterization of 1-and 4-(purinyl) triazoles

Itedale Namro Redwan, David Bliman, Munefumi Tokugawa et al
Tetrahedron. Vol. 69 (42), p. 8857-8864
Journal article
2013

Effect of MAPK Inhibitor on the Arsenite uptake by Aquaglyceroporin in Single Yeast Cells.

Doryaneh Ahmadpour, Amin Abbaszadehbanaeiyan, Morten Grötli et al
Optical Molecular Probes, Imaging and Drug Delivery, p. Page MM2C.5-
Conference contribution
2012

Solid-Phase Synthesis of 5 '-O- N-(Acyl)sulfamoyl adenosine Derivatives

Itedale Namro Redwan, Hanna Jacobson Ingemyr, Thomas Ljungdahl et al
European Journal of Organic Chemistry. Vol. 2012 (19), p. 3665-3669
Journal article
2012

Determination of primary sequence specificity of Arabidopsis MAPKs MPK3 and MPK6 leads to identification of new substrates.

Carolin Sörensson, Marit Lenman, Jenny Veide Vilg et al
Biochemical Journal. Vol. 446 (2), p. 271-8
Journal article
2012

Design and evaluation of a microfluidic system for inhibition studies of yeast cell signaling

Charlotte Hamngren Blomqvist, Peter Dinér, Morten Grötli et al
Proceedings of SPIE - The International Society for Optical Engineering. Vol. 8458
Paper in proceedings
2011

Characterization of photophysical and base-mimicking properties of a novel fluorescent adenine analogue in DNA

Anke Dierckx, Peter Dinér, Afaf El-Sagheer et al
Nucleic Acids Research. Vol. 39 (10), p. 4513-4524
Journal article
2011

Design, synthesis, and characterization of a highly effective Hog1 inhibitor: a powerful tool for analyzing MAP kinase signaling in yeast.

Peter Dinér, Jenny Veide Vilg, Jimmy Kjellén et al
PLoS ONE. Vol. 6 (5), p. e20012-
Journal article
2010

Design, synthesis and characterization of a highly effective Hog1 inhibitor: a powerful tool for analyzing MAP kinase signalling in yeast

Peter Dinér, Jenny Veide Vilg, Jimmy Kjellén et al
35th FEBS Congress, Gothenburg, Sweden
Conference poster
2010

Positional Scanning Peptide Libraries for Kinase Substrate Specificity Determinations: Straightforward and Reproducible Synthesis Using Pentafluorophenyl Esters.

Thomas Ljungdahl, Jenny Veide Vilg, Fredrik Wallner et al
Journal of Combinatorial Chemistry. Vol. 12 (5), p. 733-742
Journal article
2010

Design, synthesis and characterization of a highly effective Hog1 inhibitor: a powerful tool for analyzing MAP kinase signalling in yeast

Peter Dinér, Jenny Veide Vilg, Jimmy Kjellén et al
Yeast Genetics and Molecular Biology Meeting, Vancouver, Canada
Conference poster
2009

Short cut to 1,2,3-triazole-based p38 MAP kinase inhibitors via [3+2]-cycloaddition chemistry

Peter Dinér, Terese Andersson, Jimmy Kjellén et al
New J. Chem.,. Vol. 33, p. 1010-1016
Journal article
2009

Highly selective, cell-permeable and fast-acting wild-type Hog1 inhibitors as tools for studying cellular function of kinases

Peter Dinér, Jenny Veide Vilg, Jimmy Kjellén et al
Functional Genomics Symposium: Chemical Biology – Molecules to Probe Life, Gothenburg, Sweden
Conference contribution
2009

Synthesis and use of positional scanning peptide libraries for determination of kinase substrate consensus sequences

Jenny Veide Vilg, Thomas Ljungdahl, Markus J. Tamás et al
Functional Genomics Symposium: Chemical Biology – Molecules to Probe Life, Gothenburg, Sweden
Conference contribution
2009

2,6,8-Trisubstituted 3-hydroxychromone derivatives as fluorophores for live-cell imaging.

Christine Dyrager, Annika Friberg, Kristian Dahlén et al
Chemistry - A European Journal. Vol. 15 (37), p. 9417-23
Journal article
2009

Synthesis and Photophysical Characterisation of Fluorescent 8-(1H-1,2,3-Triazol-4-yl)adenosine Derivatives

Christine Dyrager, Karl Börjesson, P. Diner et al
European Journal of Organic Chemistry (10), p. 1515-1521
Journal article
2008

Specificity of MAP kinase substrates – determination of consensus sequences using positional scanning peptide libraries

Jenny Veide Vilg, Thomas Ljungdahl, Morten Grötli et al
Yeast Genetics and Molecular Biology Meeting, Toronto, Canada
Conference contribution

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