Metabolic Engineering of Yeast
Book chapter, 2021

This chapter focuses on a few examples that can serve as illustrations of how powerful yeast metabolic engineering stands today. Yeast, especially S. cerevisiae, plays an essential role in bioethanol production. Rapid ethanol production by yeast cells makes the fermentation process less susceptible to contamination. Higher alcohols are attractive due to some advantages compared with bioethanol, such as higher energy density, better blending into gasoline, higher octane value, lower hygroscopicity, and less corrosivity. The ethanol production process in the industry is mainly achieved through simultaneous saccharification and fermentation. Production of insulin, by volume the largest pharmaceutical protein produced, has paved the way for a wide use of S. cerevisiae for production of recombinant proteins. Virus like particles are proteins of virus capsid, which are produced by recombinant DNA technology and are important for the development of viral vaccines as they can self-assemble and display similar immunogenic properties as native viruses.

ethanol production process

DNA technology

fermentation process

yeast metabolic engineering

virus like particles

Author

Rui Pereira

Chalmers, Biology and Biological Engineering, Systems and Synthetic Biology

Olena Ishchuk

Chalmers, Biology and Biological Engineering, Systems and Synthetic Biology

Xiaowei Li

Chalmers, Biology and Biological Engineering, Systems and Synthetic Biology

Quanli Liu

Chalmers, Biology and Biological Engineering, Systems and Synthetic Biology

Yi Liu

Chalmers, Biology and Biological Engineering, Systems and Synthetic Biology

Maximilian Otto

Chalmers, Biology and Biological Engineering, Systems and Synthetic Biology

Yun Chen

Chalmers, Biology and Biological Engineering, Systems and Synthetic Biology

Verena Siewers

Chalmers, Biology and Biological Engineering, Systems and Synthetic Biology

Jens B Nielsen

BioInnovation Institute

Novo Nordisk Foundation

Chalmers, Biology and Biological Engineering, Systems and Synthetic Biology

Metabolic Engineering: Concepts and Applications: Volume 13a and 13b

Vol. 13 689-733
9783527823468 (ISBN)

Subject Categories

Chemical Process Engineering

Biocatalysis and Enzyme Technology

Other Industrial Biotechnology

DOI

10.1002/9783527823468.ch18

More information

Latest update

7/12/2024