Florian David

Associate Professor at Systems and Synthetic Biology

Source: chalmers.se

Contact Details ORCID

Publications (32)
Projects (6)

Showing 32 publications

2025

PepINVENT: generative peptide design beyond natural amino acids

Gökçe Geylan, Jon Paul Janet, Alessandro Tibo et al

Chemical Science. Vol. 16 (20), p. 8682-8696

Journal article

Show project

2025

ChIP-exo and CRISPRi/a illuminate the role of Pdr1 and Yap1 in acetic acid tolerance in <i>Saccharomyces cerevisiae</i>

Ibai Lenitz Etxaburu, Christoph Sebastian Börlin, Luca Torello Pianale et al

Applied and Environmental Microbiology. Vol. 91 (4)

Journal article

Show project

2025

Development of a yeast-based sensor platform for evaluation of ligands recognized by the human free fatty acid 2 receptor

Andrea Clausen Lind, Davi de Castro Gomes, Ricardo Bisquert Alcaraz et al

FEMS Yeast Research. Vol. 25

Journal article

Show project

2024

Evaluation and comparison of colorimetric outputs for yeast-based biosensors in laboratory and point-of-use settings

Andrea Clausen Lind, Florian David, Verena Siewers

FEMS Microbiology Letters. Vol. 371

Journal article

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2024

A methodology to correctly assess the applicability domain of cell membrane permeability predictors for cyclic peptides

Gökçe Geylan, Leonardo De Maria, Ola Engkvist et al

Digital Discovery. Vol. 3 (9), p. 1761-1775

Journal article

2023

Multiplexed Guide RNA Expression Leads to Increased Mutation Frequency in Targeted Window Using a CRISPR-Guided Error-Prone DNA Polymerase in Saccharomyces cerevisiae

Michael Gossing, Angelo Limeta, Christos Skrekas et al

ACS Synthetic Biology. Vol. 12 (8), p. 2271-2277

Journal article

2023

Targeted In Vivo Mutagenesis in Yeast Using CRISPR/Cas9 and Hyperactive Cytidine and Adenine Deaminases

Christos Skrekas, Angelo Limeta, Verena Siewers et al

ACS Synthetic Biology. Vol. 12 (8), p. 2278-2289

Journal article

2022

Controlling gene expression with deep generative design of regulatory DNA

Jan Zrimec, Xiaozhi Fu, Muhammad Azam Sheikh et al

Nature Communications. Vol. 13 (1), p. 5099-

Journal article

2022

Fluorescence-Activated Cell Sorting as a Tool for Recombinant Strain Screening

Christos Skrekas, Raphael Ferreira, Florian David

Methods in Molecular Biology. Vol. 2513, p. 39-57

Book chapter

2022

Genetically Encoded Whole Cell Biosensor for Drug Discovery of HIF-1 Interaction Inhibitors

Louis Scott, Mark J. Wigglesworth, Verena Siewers et al

ACS Synthetic Biology. Vol. 11 (10), p. 3182-3189

Journal article

2021

Expansion of the Yeast Modular Cloning Toolkit for CRISPR-Based Applications, Genomic Integrations and Combinatorial Libraries

Maximilian Otto, Christos Skrekas, Michael Gossing et al

ACS Synthetic Biology. Vol. 10 (12), p. 3461-3474

Journal article

2021

Rational gRNA design based on transcription factor binding data

David Bergenholm, Yasaman Dabirian, Raphael Ferreira et al

Synthetic Biology. Vol. 6 (1)

Journal article

2021

A Perspective on Synthetic Biology in Drug Discovery and Development - Current Impact and Future Opportunities

Florian David, Andrew M. Davis, Michael Gossing et al

SLAS Discovery. Vol. 26 (5), p. 581-603

Review article

2020

Does co-expression of Yarrowia lipolytica genes encoding Yas1p, Yas2p and Yas3p make a potential alkane-responsive biosensor in Saccharomyces cerevisiae?

Yasaman Dabirian, Christos Skrekas, Florian David et al

PLoS ONE. Vol. 15 (12 December)

Journal article

2019

FadR-Based Biosensor-Assisted Screening for Genes Enhancing Fatty Acyl-CoA Pools in Saccharomyces cerevisiae

Yasaman Dabirian, Paulo Teixeira, Jens B Nielsen et al

ACS Synthetic Biology. Vol. 8 (8), p. 1788-1800

Journal article

2019

Integration of a multi-step heterologous pathway in Saccharomyces cerevisiae for the production of abscisic acid

Maximilian Otto, Paulo Teixeira, Maria Vizcaino et al

Microbial Cell Factories. Vol. 18 (1)

Journal article

2019

Model-Assisted Fine-Tuning of Central Carbon Metabolism in Yeast through dCas9-Based Regulation

Raphael Ferreira, Christos Skrekas, Alex Hedin et al

ACS Synthetic Biology. Vol. 8 (11), p. 2457-2463

Journal article

2019

Increasing jojoba-like wax ester production in Saccharomyces cerevisiae by enhancing very long-chain, monounsaturated fatty acid synthesis

Leonie Wenning, Christer S. Ejsing, Florian David et al

Microbial Cell Factories. Vol. 18 (1)

Journal article

2019

Expanding the Dynamic Range of a Transcription Factor-Based Biosensor in Saccharomyces cerevisiae

Yasaman Dabirian, Xiaowei Li, Yun Chen et al

ACS Synthetic Biology. Vol. 8 (9), p. 1968-1975

Journal article

2018

Reprogramming Yeast Metabolism from Alcoholic Fermentation to Lipogenesis

Tao Yu, Yongjin Zhou, Mingtao Huang et al

Cell. Vol. 174 (6), p. 1549-1572

Journal article

2018

Metabolic engineering of Saccharomyces cerevisiae for overproduction of triacylglycerols

Raphael Ferreira, Paulo Teixeira, Michael Gossing et al

Metabolic Engineering Communications. Vol. 6, p. 22-27

Journal article

2018

Advancing biotechnology with CRISPR/Cas9: recent applications and patent landscape

Raphael Ferreira, Florian David, Jens B Nielsen

Journal of Industrial Microbiology and Biotechnology. Vol. 45 (7), p. 467-480

Review article

2018

Engineering lipid droplet assembly mechanisms for improved triacylglycerol accumulation in Saccharomyces cerevisiae

Paulo Teixeira, Florian David, Verena Siewers et al

FEMS Yeast Research. Vol. 18 (6)

Journal article

2018

Multiplexed CRISPR/Cas9 Genome Editing and Gene Regulation Using Csy4 in Saccharomyces cerevisiae

Raphael Ferreira, Christos Skrekas, Jens B Nielsen et al

ACS Synthetic Biology. Vol. 7 (1), p. 10-15

Journal article

2017

Metabolic engineering of Saccharomyces cerevisiae for production of very long chain fatty acid-derived chemicals

Tao Yu, Yongjin Zhou, Leonie Wenning et al

Nature Communications. Vol. 8, p. Article number: 15587-

Journal article

Show project

2017

Affibody Scaffolds Improve Sesquiterpene Production in Saccharomyces cerevisiae.

Stefan Tippmann, J. Anfelt, Florian David et al

ACS Synthetic Biology. Vol. 6 (1), p. 19-28

Journal article

2017

Transcriptional reprogramming in yeast using dCas9 and combinatorial gRNA strategies

E. D. Jensen, Raphael Ferreira, T. Jakociunas et al

Microbial Cell Factories. Vol. 16 (1), p. 46-

Journal article

2017

Establishing very long-chain fatty alcohol and wax ester biosynthesis in Saccharomyces cerevisiae

Leonie Wenning, Tao Yu, Florian David et al

Biotechnology and Bioengineering. Vol. 114 (5), p. 1025-1035

Journal article

Show project

2016

Flux Control at the Malonyl-CoA Node through Hierarchical Dynamic Pathway Regulation in Saccharomyces cerevisiae

Florian David, Jens B Nielsen, Verena Siewers

ACS Synthetic Biology. Vol. 5 (3), p. 224-233

Journal article

2015

Advances in yeast genome engineering

Florian David, Verena Siewers

FEMS Yeast Research. Vol. 15 (1)

Journal article

2015

Impact of synthetic biology and metabolic engineering on industrial production of fine chemicals

David Jullesson, Florian David, B. F. Pfleger et al

Biotechnology Advances. Vol. 33 (7), p. 1395-1402

Review article

2014

EasyClone: method for iterative chromosomal integration of multiple genes in Saccharomyces cerevisiae

N. B. Jensen, T. Strucko, K. R. Kildegaard et al

FEMS Yeast Research. Vol. 14 (2), p. 238-248

Journal article

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Showing 6 research projects

2022–2025

Development of a platform yeast strain for cytochrome P450-containing pathway

Verena Siewers Systems and Synthetic Biology

Florian David Systems and Synthetic Biology

Swedish Research Council (VR)

2021–2025

AI-guidad design för cykliska peptidläkemedel

Florian David Systems and Synthetic Biology

Swedish Foundation for Strategic Research (SSF)

1 publication exists

2020–2022

Nya läkemedel som blockerar SARS-CoV-2 infektion

Florian David Systems and Synthetic Biology

VINNOVA

2019–2023

CRISPRi for elucidating stress regulation in yeast

Yvonne Nygård Industrial Biotechnology

Florian David Systems and Synthetic Biology

Verena Siewers Systems and Synthetic Biology

Ibai Lenitz Etxaburu Industrial Biotechnology

Christoph Sebastian Börlin Systems and Synthetic Biology

Vaskar Mukherjee Industrial Biotechnology

Swedish Research Council (VR)

1 publication exists

2018–2021

CRISPR/dCAS9 mediated in vivo enzyme engineering in yeast cell factories

Florian David Systems and Synthetic Biology

ÅForsk

2018–

Biofuel production with yeast – Boosting alkane production through enzyme engineering

Verena Siewers Systems and Synthetic Biology

Florian David Systems and Synthetic Biology

Chalmers

There might be more projects where Florian David participates, but you have to be logged in as a Chalmers employee to see them.