Florian David

Docent vid Systembiologi

Källa: chalmers.se

Kontaktuppgifter ORCID

Publikationer (29)
Projekt (6)

Visar 29 publikationer

2024

Evaluation and comparison of colorimetric outputs for yeast-based biosensors in laboratory and point-of-use settings

Andrea Clausen Lind, Florian David, Verena Siewers

FEMS Microbiology Letters. Vol. 371

Artikel i vetenskaplig tidskrift

Visa projekt

2024

A methodology to correctly assess the applicability domain of cell membrane permeability predictors for cyclic peptides

Gökçe Geylan, Leonardo De Maria, Ola Engkvist et al

Digital Discovery. Vol. 3 (9), p. 1761-1775

Artikel i vetenskaplig tidskrift

2023

Multiplexed Guide RNA Expression Leads to Increased Mutation Frequency in Targeted Window Using a CRISPR-Guided Error-Prone DNA Polymerase in Saccharomyces cerevisiae

Michael Gossing, Angelo Limeta, Christos Skrekas et al

ACS Synthetic Biology. Vol. 12 (8), p. 2271-2277

Artikel i vetenskaplig tidskrift

2023

Targeted In Vivo Mutagenesis in Yeast Using CRISPR/Cas9 and Hyperactive Cytidine and Adenine Deaminases

Christos Skrekas, Angelo Limeta, Verena Siewers et al

ACS Synthetic Biology. Vol. 12 (8), p. 2278-2289

Artikel i vetenskaplig tidskrift

2022

Controlling gene expression with deep generative design of regulatory DNA

Jan Zrimec, Xiaozhi Fu, Muhammad Azam Sheikh et al

Nature Communications. Vol. 13 (1), p. 5099-

Artikel i vetenskaplig tidskrift

2022

Fluorescence-Activated Cell Sorting as a Tool for Recombinant Strain Screening

Christos Skrekas, Raphael Ferreira, Florian David

Methods in Molecular Biology. Vol. 2513, p. 39-57

Kapitel i bok

2022

Genetically Encoded Whole Cell Biosensor for Drug Discovery of HIF-1 Interaction Inhibitors

Louis Scott, Mark J. Wigglesworth, Verena Siewers et al

ACS Synthetic Biology. Vol. 11 (10), p. 3182-3189

Artikel i vetenskaplig tidskrift

2021

Expansion of the Yeast Modular Cloning Toolkit for CRISPR-Based Applications, Genomic Integrations and Combinatorial Libraries

Maximilian Otto, Christos Skrekas, Michael Gossing et al

ACS Synthetic Biology. Vol. 10 (12), p. 3461-3474

Artikel i vetenskaplig tidskrift

2021

Rational gRNA design based on transcription factor binding data

David Bergenholm, Yasaman Dabirian, Raphael Ferreira et al

Synthetic Biology. Vol. 6 (1)

Artikel i vetenskaplig tidskrift

2021

A Perspective on Synthetic Biology in Drug Discovery and Development - Current Impact and Future Opportunities

Florian David, Andrew M. Davis, Michael Gossing et al

SLAS Discovery. Vol. 26 (5), p. 581-603

Reviewartikel

2020

Does co-expression of Yarrowia lipolytica genes encoding Yas1p, Yas2p and Yas3p make a potential alkane-responsive biosensor in Saccharomyces cerevisiae?

Yasaman Dabirian, Christos Skrekas, Florian David et al

PLoS ONE. Vol. 15 (12 December)

Artikel i vetenskaplig tidskrift

2019

FadR-Based Biosensor-Assisted Screening for Genes Enhancing Fatty Acyl-CoA Pools in Saccharomyces cerevisiae

Yasaman Dabirian, Paulo Teixeira, Jens B Nielsen et al

ACS Synthetic Biology. Vol. 8 (8), p. 1788-1800

Artikel i vetenskaplig tidskrift

2019

Integration of a multi-step heterologous pathway in Saccharomyces cerevisiae for the production of abscisic acid

Maximilian Otto, Paulo Teixeira, Maria Vizcaino et al

Microbial Cell Factories. Vol. 18 (1)

Artikel i vetenskaplig tidskrift

2019

Model-Assisted Fine-Tuning of Central Carbon Metabolism in Yeast through dCas9-Based Regulation

Raphael Ferreira, Christos Skrekas, Alex Hedin et al

ACS Synthetic Biology. Vol. 8 (11), p. 2457-2463

Artikel i vetenskaplig tidskrift

2019

Increasing jojoba-like wax ester production in Saccharomyces cerevisiae by enhancing very long-chain, monounsaturated fatty acid synthesis

Leonie Wenning, Christer S. Ejsing, Florian David et al

Microbial Cell Factories. Vol. 18 (1)

Artikel i vetenskaplig tidskrift

2019

Expanding the Dynamic Range of a Transcription Factor-Based Biosensor in Saccharomyces cerevisiae

Yasaman Dabirian, Xiaowei Li, Yun Chen et al

ACS Synthetic Biology. Vol. 8 (9), p. 1968-1975

Artikel i vetenskaplig tidskrift

2018

Reprogramming Yeast Metabolism from Alcoholic Fermentation to Lipogenesis

Tao Yu, Yongjin Zhou, Mingtao Huang et al

Cell. Vol. 174 (6), p. 1549-1572

Artikel i vetenskaplig tidskrift

2018

Metabolic engineering of Saccharomyces cerevisiae for overproduction of triacylglycerols

Raphael Ferreira, Paulo Teixeira, Michael Gossing et al

Metabolic Engineering Communications. Vol. 6, p. 22-27

Artikel i vetenskaplig tidskrift

2018

Advancing biotechnology with CRISPR/Cas9: recent applications and patent landscape

Raphael Ferreira, Florian David, Jens B Nielsen

Journal of Industrial Microbiology and Biotechnology. Vol. 45 (7), p. 467-480

Reviewartikel

2018

Engineering lipid droplet assembly mechanisms for improved triacylglycerol accumulation in Saccharomyces cerevisiae

Paulo Teixeira, Florian David, Verena Siewers et al

FEMS Yeast Research. Vol. 18 (6)

Artikel i vetenskaplig tidskrift

2018

Multiplexed CRISPR/Cas9 Genome Editing and Gene Regulation Using Csy4 in Saccharomyces cerevisiae

Raphael Ferreira, Christos Skrekas, Jens B Nielsen et al

ACS Synthetic Biology. Vol. 7 (1), p. 10-15

Artikel i vetenskaplig tidskrift

2017

Metabolic engineering of Saccharomyces cerevisiae for production of very long chain fatty acid-derived chemicals

Tao Yu, Yongjin Zhou, Leonie Wenning et al

Nature Communications. Vol. 8, p. Article number: 15587-

Artikel i vetenskaplig tidskrift

Visa projekt

2017

Affibody Scaffolds Improve Sesquiterpene Production in Saccharomyces cerevisiae.

Stefan Tippmann, J. Anfelt, Florian David et al

ACS Synthetic Biology. Vol. 6 (1), p. 19-28

Artikel i vetenskaplig tidskrift

2017

Transcriptional reprogramming in yeast using dCas9 and combinatorial gRNA strategies

E. D. Jensen, Raphael Ferreira, T. Jakociunas et al

Microbial Cell Factories. Vol. 16 (1), p. 46-

Artikel i vetenskaplig tidskrift

2017

Establishing very long-chain fatty alcohol and wax ester biosynthesis in Saccharomyces cerevisiae

Leonie Wenning, Tao Yu, Florian David et al

Biotechnology and Bioengineering. Vol. 114 (5), p. 1025-1035

Artikel i vetenskaplig tidskrift

Visa projekt

2016

Flux Control at the Malonyl-CoA Node through Hierarchical Dynamic Pathway Regulation in Saccharomyces cerevisiae

Florian David, Jens B Nielsen, Verena Siewers

ACS Synthetic Biology. Vol. 5 (3), p. 224-233

Artikel i vetenskaplig tidskrift

2015

Advances in yeast genome engineering

Florian David, Verena Siewers

FEMS Yeast Research. Vol. 15 (1)

Artikel i vetenskaplig tidskrift

2015

Impact of synthetic biology and metabolic engineering on industrial production of fine chemicals

David Jullesson, Florian David, B. F. Pfleger et al

Biotechnology Advances. Vol. 33 (7), p. 1395-1402

Reviewartikel

2014

EasyClone: method for iterative chromosomal integration of multiple genes in Saccharomyces cerevisiae

N. B. Jensen, T. Strucko, K. R. Kildegaard et al

FEMS Yeast Research. Vol. 14 (2), p. 238-248

Artikel i vetenskaplig tidskrift

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Visar 6 forskningsprojekt

2022–2025

Utveckling av en jäststam som plattform för cytokrom P450 baserade reaktionsvägar

Verena Siewers Systembiologi

Florian David Systembiologi

Vetenskapsrådet (VR)

2021–2025

AI-guidad design för cykliska peptidläkemedel

Florian David Systembiologi

Stiftelsen för Strategisk forskning (SSF)

2020–2022

Novel drug modalities blocking SARS-CoV-2 infection

Florian David Systembiologi

VINNOVA

2019–2023

Kartläggning av stressreglering i jäst genom CRISPRi

Yvonne Nygård Industriell bioteknik

Florian David Systembiologi

Verena Siewers Systembiologi

Ibai Lenitz Etxaburu Industriell bioteknik

Christoph Sebastian Börlin Systembiologi

Vaskar Mukherjee Industriell bioteknik

Vetenskapsrådet (VR)

2018–2021

CRISPR/dCAS9 mediated in vivo enzyme engineering in yeast cell factories

Florian David Systembiologi

ÅForsk

2018–

Biofuel production with yeast – Boosting alkane production through enzyme engineering

Verena Siewers Systembiologi

Florian David Systembiologi

Chalmers

Det kan finnas fler projekt där Florian David medverkar, men du måste vara inloggad som anställd på Chalmers för att kunna se dem.