Anna Johnning

Forskare at Applied Mathematics and Statistics

Antibiotics are used to treat and prevent bacterial infections. However, the high consumption has resulted in an increased prevalence of antibiotic resistance – when bacteria evolve so that antibiotic treatment is no longer effective – which is one of the major threats to human health today. The changes can occur through mutations in the bacterial DNA or through the acquisition of mobile antibiotic resistance genes. My research focuses on developing methods with clinical applications for improved diagnostics of bacterial infections. Better and faster diagnostics will reduce our use of antibiotics and, thereby, slow the increase and spread of resistance. I am especially interested in bioinformatic analyses of DNA sequencing data and optical DNA maps (ODM.


Showing 15 publications


Discovery of Species-unique Peptide Biomarkers of Bacterial Pathogens by Tandem Mass Spectrometry-based Proteotyping

Roger Karlsson, Annika Thorsell, Margarita Gomila et al
Molecular and Cellular Proteomics. Vol. 19 (3), p. 518-528
Journal article

Parameter Estimation for Nonlinear Mixed Effects Models Implemented in Mathematica

Jacob Leander, Joachim Almquist, Helga Kristín Ólafsdóttir et al
Conference poster

The resistomes of six carbapenem-resistant pathogens - a critical genotype-phenotype analysis

Anna Johnning, N. Karami, Erika Tång Hallbäck et al
Microbial Genomics. Vol. 4 (11)
Journal article

Typing and Characterization of Bacteria Using Bottom-up Tandem Mass Spectrometry Proteomics

Fredrik Boulund, R. Karlsson, L. Gonzales-Siles et al
Molecular and Cellular Proteomics. Vol. 16 (6), p. 1052-1063
Journal article

Strategies to improve usability and preserve accuracy in biological sequence databases

Johan Bengtsson-Palme, Fredrik Boulund, Robert Edström et al
Proteomics. Vol. 16 (18), p. 2454-2460
Journal article

Draft genome sequence of extended-spectrum-β-lactamase-producing Escherichia coli strain CCUG 62462, isolated from a urine sample

Anna Johnning, Hedvig E Jakobsson, Fredrik Boulund et al
Genome Announcements. Vol. 4 (6), p. e01382-16
Journal article

Isolation of novel IncA/C and IncN fluoroquinolone resistance plasmids from an antibiotic-polluted lake

Carl-Fredrik Flach, Anna Johnning, Ida Nilsson et al
Journal of Antimicrobial Chemotherapy. Vol. 70 (10), p. 2709-2717
Journal article

Resistance Mutations in gyrA and parC are Common in Escherichia Communities of both Fluoroquinolone-Polluted and Uncontaminated Aquatic Environments

Anna Johnning, Erik Kristiansson, Jerker Fick et al
Frontiers in Microbiology. Vol. 6 (DEC), p. 1355-
Journal article

Quinolone resistance mutations in the faecal microbiota of Swedish travellers to India

Anna Johnning, Erik Kristiansson, Martin Angelin et al
BMC Microbiology. Vol. 15 (1), p. Article Number: 235 -
Journal article

Acquired genetic mechanisms of a multiresistant bacterium isolated from a treatment plant receiving wastewater from antibiotic production.

Anna Johnning, Edward R.B. Moore, Liselott Svensson-Stadler et al
Applied and Environmental Microbiology. Vol. 79 (23), p. 7256-63
Journal article

A novel method to discover fluoroquinolone antibiotic resistance (qnr) genes in fragmented nucleotide sequences

Fredrik Boulund, Anna Johnning, Mariana Buongermino Pereira et al
BMC Genomics. Vol. 13 (1), p. 695-
Journal article

Exploring the metagenomes of environmental antibiotic hotspots to identify resistance factors that we may face in the clinic tomorrow

D. G. Joakim Larsson, Anders Janzon, Anna Johnning et al
SETAC Europe 21st Annual Meeting; Ecosystem Protection in a Sustainable World: A challenge for Science and Regulation 15-19 May 2011, p. 38-
Conference poster

The genome of an extensively drug-resistant bacterium isolated from a wastewater treatment plant receiving effluent from antibiotic manufacturing

Anna Johnning, Erik Kristiansson, Y. Shouche et al
SETAC Europe 21st Annual Meeting; Ecosystem Protection in a Sustainable World: A challenge for Science and Regulation 15-19 May 2011, p. 212-
Conference poster

Whole genome sequencing of a multiresistant bacterium isolated from a wastewater treatment plant receiving effluent from antibiotic drug manufactureing

Anna Johnning, Erik Kristiansson, Y.S Shouche et al
35th Congress of the Federation of European Biochemical Societies (FEBS), Gothenburg, June 26 - July 1, 2010. Vol. 277 (Suppl 1), p. 105-
Conference poster

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