Jörg Hanrieder

2023

Investigating New Applications of a Photoswitchable Fluorescent Norbornadiene as a Multifunctional Probe for Delineation of Amyloid Plaque Polymorphism

GM1 locates to mature amyloid structures implicating a prominent role for glycolipid-protein interactions in Alzheimer pathology

Association of PTHrP levels in CSF with Alzheimer's disease biomarkers

2019

Molecular imaging mass spectrometry for probing protein dynamics in neurodegenerative disease pathology

Multimodal Chemical Imaging of Amyloid Plaque Polymorphism Reveals Aβ Aggregation Dependent Anionic Lipid Accumulations and Metabolism

2017

Lithium Accumulates in Neurogenic Brain Regions as Revealed by High Resolution Ion Imaging

2017

Delineating Amyloid Plaque Associated Neuronal Sphingolipids in Transgenic Alzheimer's Disease Mice (tgArcSwe) Using MALDI Imaging Mass Spectrometry

MALDI imaging delineates hippocampal glycosphingolipid changes associated with neurotoxin induced proteopathy following neonatal BMAA exposure

Probing Amyloid-β Pathology in transgenic Alzheimer's disease (tgArcSwe) mice using MALDI Imaging Mass Spectrometry

2015

Intracellular fibril formation, calcification, and enrichment of chaperones, cytoskeletal, and intermediate filament proteins in the adult hippocampus CA1 following neonatal exposure to the nonprotein amino acid BMAA

Dietary uptake of omega-3 fatty acids in mouse tissue studied by time-of-flight secondary ion mass spectrometry (TOF-SIMS)

Spatial neuroproteomics using imaging mass spectrometry

2014

Spatial Elucidation of Spinal Cord Lipid- and Metabolite-Regulations in Amyotrophic Lateral Sclerosis

2014

Using imaging ToF-SIMS data to determine the cell wall thickness of fibers in wood

High Resolution Metabolite Imaging in the Hippocampus Following Neonatal Exposure to the Environmental Toxin BMAA Using ToF-SIMS

Probing the lipid chemistry of neurotoxin-induced hippocampal lesions using multimodal imaging mass spectrometry

Cerebrospinal fluid proteome analysis reveals differentially abundant proteins in multiple sclerosis

2014

Comprehensive multiplexed protein quantitation delineates eosinophilic and neutrophilic experimental asthma

Glycoprotein 130 promotes human blastocyst development in vitro

Capillary Electrophoresis-Mass Spectrometry-Based Detection of Drugs and Neurotransmitters in Drosophila Brain

Imaging mass spectrometry in neuroscience.

Time-of-Flight Secondary Ion Mass Spectrometry Based Molecular Histology of Human Spinal Cord Tissue and Motor Neurons

MALDI imaging of post-mortem human spinal cord in amyotrophic lateral sclerosis

Freeze-Drying as Sample Preparation for Micellar Electrokinetic Capillary Chromatography-Electrochemical Separations of Neurochemicals in Drosophila Brains

Analysis of neuropeptides by MALDI imaging mass spectrometry.

Proteins in aqueous humor from cataract patients with and without pseudoexfoliation syndrome.

2012

Proteomic Analysis of Cerebrospinal Fluid in a Fulminant Case of Multiple Sclerosis

Neonatal exposure to the cyanobacterial toxin BMAA induces changes in protein expression and neurodegeneration in adult hippocampus.

MALDI imaging mass spectrometry of neuropeptides in Parkinson's disease

Imaging mass spectrometry reveals elevated nigral levels of dynorphin neuropeptides in L-DOPA-induced dyskinesia in rat model of Parkinson's disease.

MALDI mass spectrometry based molecular phenotyping of CNS glial cells for prediction in mammalian brain tissue.

L-DOPA-induced dyskinesia is associated with regional increase of striatal dynorphin peptides as elucidated by imaging mass spectrometry.

Assessment of the partitioning capacity of high abundant proteins in human cerebrospinal fluid using affinity and immunoaffinity subtraction spin columns.

CE MALDI-TOF/TOF MS for multiplexed quantification of proteins in human ventricular cerebrospinal fluid.

Development of affinity columns for the removal of high-abundance proteins in cerebrospinal fluid.

Temporally resolved differential proteomic analysis of human ventricular CSF for monitoring traumatic brain injury biomarker candidates.

Protein content in aqueous humor from patients with pseudoexfoliation (PEX) investigated by capillary LC MALDI-TOF/TOF MS.

Surface modified capillary electrophoresis combined with in solution isoelectric focusing and MALDI-TOF/TOF MS: a gel-free multidimensional electrophoresis approach for proteomic profiling--exemplified on human follicular fluid.

Clinical perspectives of high-resolution mass spectrometry-based proteomics in neuroscience: exemplified in amyotrophic lateral sclerosis biomarker discovery research.

Proteomic analysis of human follicular fluid using an alternative bottom-up approach.

Proteome profiling of human cerebrospinal fluid: exploring the potential of capillary electrophoresis with surface modified capillaries for analysis of complex biological samples.

Proteomic characterization of IgY preparations purified with a water dilution method.

Expression and purification of catalytically active human PHD3 in Escherichia coli.

Focused proteomics in post-mortem human spinal cord.