Yu Chen
Showing 30 publications
Relieving metabolic burden to improve robustness and bioproduction by industrial microorganisms
Single-cell omics analysis with genome-scale metabolic modeling
Engineering yeast mitochondrial metabolism for 3-hydroxypropionate production
Genome-scale metabolic models applied for human health and biopharmaceutical engineering
Flux regulation through glycolysis and respiration is balanced by inositol pyrophosphates in yeast
Engineering yeast for high-level production of diterpenoid sclareol
GotEnzymes: an extensive database of enzyme parameter predictions
Deep learning-based k(cat) prediction enables improved enzyme-constrained model reconstruction
Genome-scale modeling of yeast metabolism: retrospectives and perspectives
Engineering cofactor supply and recycling to drive phenolic acid biosynthesis in yeast
Yeast has evolved to minimize protein resource cost for synthesizing amino acids
Proteome Constraints in Genome-Scale Models
Engineering yeast metabolism for the discovery and production of polyamines and polyamine analogues
In vitro turnover numbers do not reflect in vivo activities of yeast enzymes
Mathematical modeling of proteome constraints within metabolism
Yeast optimizes metal utilization based on metabolic network and enzyme kinetics
Proteome constraints reveal targets for improving microbial fitness in nutrient-rich environments
Yeast metabolic innovations emerged via expanded metabolic network and gene positive selection
Genome-scale modeling for Bacillus coagulans to understand the metabolic characteristics
Energy metabolism controls phenotypes by protein efficiency and allocation
Rewiring carbon metabolism in yeast for high level production of aromatic chemicals
Systematic inference of functional phosphorylation events in yeast metabolism
Flux control through protein phosphorylation in yeast
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