Elin Esbjörner Winters

Probing physical properties of single amyloid fibrils using nanofluidic channels

Supported Lipid Bilayer Platform for Characterization of Lipid Nanoparticle-Based Endosomal Escape Mechanism

2023

Monovalent cations have different effects on the assembly kinetics and morphology of α-synuclein amyloid fibrils

2023

Ginsenoside Rg3 Reduces the Toxicity of Graphene Oxide Used for pH-Responsive Delivery of Doxorubicin to Liver and Breast Cancer Cells

Pore formation by melittin in porous silica-supported lipid membranes

2022

Label-free nanofluidic scattering microscopy of size and mass of single diffusing molecules and nanoparticles

2022

Novel endosomolytic compounds enable highly potent delivery of antisense oligonucleotides

2022

Interaction Kinetics of Individual mRNA-Containing Lipid Nanoparticles with an Endosomal Membrane Mimic: Dependence on pH, Protein Corona Formation, and Lipoprotein Depletion

2022

Single-shot self-supervised object detection in microscopy

2021

A high-throughput Galectin-9 imaging assay for quantifying nanoparticle uptake, endosomal escape and functional RNA delivery

2021

Fluorescent base analogues in gapmers enable stealth labeling of antisense oligonucleotide therapeutics

2021

Stealth Fluorescence Labeling for Live Microscopy Imaging of mRNA Delivery

2021

Delivery of Oligonucleotide Therapeutics: Chemical Modifications, Lipid Nanoparticles, and Extracellular Vesicles

2020

Graphene oxide sheets and quantum dots inhibit alpha-synuclein amyloid formation by different mechanisms

2020

Lipid vesicle composition influences the incorporation and fluorescence properties of the lipophilic sulphonated carbocyanine dye SP-DiO

2020

Amyloid formation of fish β-parvalbumin involves primary nucleation triggered by disulfide-bridged protein dimers

2020

Amyloid formation of bovine insulin is retarded in moderately acidic pH and by addition of short-chain alcohols

2020

The Liver and Kidneys mediate clearance of cardiac troponin in the rat

Correlation between Cellular Uptake and Cytotoxicity of Fragmented α-Synuclein Amyloid Fibrils Suggests Intracellular Basis for Toxicity

A Nanofluidic Device for Multiplexed Analysis of Single Exosomes

2020

Novel clearance of muscle proteins by muscle cells

Independent Size and Fluorescence Emission Determination of Individual Biological Nanoparticles Reveals that Lipophilic Dye Incorporation Does Not Scale with Particle Size

2020

Role of Membrane Tension Sensitive Endocytosis and Rho GTPases in the Uptake of the Alzheimer's Disease Peptide Aβ(1-42)

2020

Redox-Dependent Copper Ion Modulation of Amyloid-β (1-42) Aggregation In Vitro

High throughput size-determination and multiplexed fluorescence analysis of single biological particles in a nanofluidic device

2019

Using Tetracysteine-Tagged TDP-43 with a Biarsenical Dye to Monitor Real-Time Trafficking in a Cell Model of Amyotrophic Lateral Sclerosis

2018

Copper Chaperone Atox1 Interacts with Cell Cycle Proteins

Cell surface proteoglycan-mediated uptake and accumulation of the Alzheimer's disease peptide Aβ(1–42)

Lipid membranes catalyse the fibril formation of the amyloid-? (1–42) peptide through lipid-fibril interactions that reinforce secondary pathways

2017

Endocytic uptake of monomeric amyloid-β peptides is clathrin- and dynamin-independent and results in selective accumulation of Aβ(1-42) compared to Aβ(1-40)

2017

A nano flow cytometer for single lipid vesicle analysis

Binding of Thioflavin-T to Amyloid Fibrils Leads to Fluorescence Self-Quenching and Fibril Compaction

Detection of amyloid-beta fibrils using the DNA-intercalating dye YOYO-1: Binding mode and fibril formation kinetics

Time-resolved thioflavin-T fluorescence-expanding the amyloid characterisation toolbox

2015

Steady-state and time-resolved Thioflavin-T fluorescence can report on morphological differences in amyloid fibrils formed by A beta(1-40) and A beta(1-42)

2015

Solvent exposure of Tyr10 as a probe of structural differences between monomeric and aggregated forms of the amyloid-β peptide

Studying Distribution and Aggregation of TDP-43 in Mammalian Cells: A Comparison between Fluorescent Protein and Tetracysteine Labelling Strategies

2014

Direct Observations of Amyloid beta Self-Assembly in Live Cells Provide Insights into Differences in the Kinetics of A beta(1-40) and A beta(1-42) Aggregation

Cell surface binding and uptake of arginine- and lysine-rich penetratin peptides in absence and presence of proteoglycans

Effects of Tryptophan Content and Backbone Spacing on the Uptake Efficiency of Cell-Penetrating Peptides

Dual functions of the human antimicrobial peptide LL-37-Target membrane perturbation and host cell cargo delivery

Assigning Membrane Binding Geometry of Cytochrome c by Polarized Light Spectroscopy

Stimulated endocytosis in penetratin uptake: Effect of arginine and lysine

DNA condensation by PAMAM dendrimers: Self-assembly characteristics and effect on transcription

Membrane binding of pH-sensitive influenza fusion peptides. Positioning, configuration, and induced leakage in a lipid vesicle model

Membrane-Active Peptides for Drug Delivery: Positioning, Structure and Interactions in Model Membranes

Membrane Interactions of Cell-Penetrating Peptides

Retinoid chromophores as probes of membrane lipid order

Tryptophan Orientation in Model Lipid Membranes

Counterion-mediated Membrane Penetration: Cationic Cell-penetrating Peptides overcome Born Energy Barrier by Ion-pairing with Phospholipids

Membrane interactions of cell-penetrating peptides probed by tryptophan fluorescence and dichroism techniques: Correlations of structure to cellular uptake

Membrane interaction properties of cell-penetrating peptides

Membrane binding and translocation of cell-penetrating peptides

Vesicle size-dependent translocation of penetratin analogs across lipid membranes

2003

Meso stereoisomer as a probe of enantioselective threading intercalation of semirigid ruthenium complex [µ-(11,11'-bidppz)(phen)4Ru2]4+