Valeria Mapelli

2022

Directed Evolution of (R)-2-Hydroxyglutarate Dehydrogenase Improves 2-Oxoadipate Reduction by 2 Orders of Magnitude

Conformational gating in ammonia lyases

2020

Structure-function investigation of 3-methylaspartate ammonia lyase reveals substrate molecular determinants for the deamination reaction

2019

Presence of galactose in precultures induces lacS and leads to short lag phase in lactose-grown Lactococcus lactis cultures

2018

Biobased adipic acid – The challenge of developing the production host

2018

In silico and in vitro studies of the reduction of unsaturated α,β bonds of trans-2-hexenedioic acid and 6-amino-trans-2-hexenoic acid – Important steps towards biobased production of adipic acid

Molecular docking and molecular dynamics approach for investigating α, β-reduction of enoate moieties: toward renewable production of adipic acid

DEAMINATION REACTIONS AS PART OF THE METABOLIC PATHWAY FOR THE PRODUCTION OF ADIPIC ACID

2018

A novel chimaeric flocculation protein enhances flocculation in Saccharomyces cerevisiae

Molecular docking and linear interaction energy studies give insight to α, β-reduction of enoate groups in enzymes

2017

Engineering ammonia-lyases for lysine transformation: first steps to green production of adipic acid

Docking and molecular dynamics approach for enzyme selection for α, β-reduction of enoate moiety : toward renewable production of adipic acid

2017

Adipic acid tolerance screening for potential adipic acid production hosts

2017

Enhancement of anaerobic lysine production in Corynebacterium glutamicum electrofermentations

Electrified fermentations enhance anaerobic lysine production by Corynebacterium glutamicum

2016

The Presence of Pretreated Lignocellulosic Solids from Birch during Saccharomyces cerevisiae Fermentations Leads to Increased Tolerance to Inhibitors - A Proteomic Study of the Effects

Biocathodes for enhancing anaerobic growth of Corynebacterium glutamicum with nitrate

2016

Respiratory metabolism and calorie restriction relieve persistent endoplasmic reticulum stress induced by calcium shortage in yeast

2016

Cathodes enhance Corynebacterium glutamicum growth with nitrate and promote acetate and formate production

Characterization of the respiratory physiology of Lactococcus lactis for starter culture production with improved acidification capacity

A FLO1 variant which yields a NewFlo phenotype

Microbial electrocatalysis for the enhancement of 1,3-propanediol production from glycerol

Electrofermentations allow for efficient conversion of waste glycerol into value-added 1,3-propanediol

2015

Electrochemical startup increases 1,3-propanediol titers in mixed-culture glycerol fermentations

What induces respiration in lactic acid bacteria? Characterization of respiratory metabolism of Lactococcus lactis in bioreactors for production of starter cultures with improved acidification capacity

Flocculation Causes Inhibitor Tolerance in Saccharomyces cerevisiae for Second-Generation Bioethanol Production

Yeast Metabolic Engineering - Methods and Protocols

METABOLIC ENGINEERING OF Saccharomyces cerevisiae FOR PRODUCTION OF ADIPIC ACID FROM RENEWABLE SOURCES ONE ROUTE TOWARDS A BIOECONOMY

METABOLIC ENGINEERING OF Saccharomyces cerevisiae FOR PRODUCTION OF ADIPIC ACID FROM RENEWABLE SOURCES

Enhancement of 1,3-propanediol production from glycerol using bioelectrochemical systems

2014

Performance and bacterial enrichment of bioelectrochemical systems during methane and acetate production

TARGETING THE INTRACELLULAR REDOX STATE IN THE DEVELOPMENT OF MORE ROBUST Saccharomyces cerevisiae STRAINS FOR LIGNOCELLULOSIC BIOETHANOL PRODUCTION

Yeast physiology studies and metabolic engineering for enhanced robustness

Improved inhibitor tolerance and simultaneous utilisation of hexoses and pentoses during fermentation of inhibitory lignocellulose hydrolysates by yeast at high local cell density

2013

Engineering glutathione biosynthesis of Saccharomyces cerevisiae increases robustness to inhibitors in pretreated lignocellulosic materials

Robust S. cerevisiae strain for next generation bio-processes: concepts and case-studies

Together we are strong – Yeast flocculation for efficient fermentation of toxic hydrolysates

Robust S. cerevisiae strain for next generation bio-processes: concepts and case-studies

Systems biology methods and developments for Saccharomyces cerevisiae and other industrial yeasts in relation to the production of fermented food and food ingredients

Exploring the capabilities of microbial electrosynthesis during treatment of low-strength wastewater

2013

Viability Study of the Use of Cast Iron Open Cell Foam as Microbial Fuel Cell Electrodes

2013

The influence of HMF and furfural on redox-balance and energy-state of xylose-utilizing Saccharomyces cerevisiae

Robust yeast strains as prerequisite for feasible biofuels production from renewable biomass resources

Evaluating methane and acetate production in microbial electrolysis cells: reactor performance and microbial diversity

Intracellular redox state as key target for Saccharomyces cerevisiae tolerance to lignocellulosic hydrolysate inhibitors

Improvement of methane generation via coupling of anaerobic digestion to Bio-Electrochemical Systems

High local cell density for efficient 2nd generation bioethanol production by Saccharomyces cerevisiae

Performance of Metal Foams as MFC Electrodes and Characterization of Waste Streams from Pulp and Paper plants in Bioelectrochemical Systems

Transcriptional response and alterations in adenonucleotides and redox cofactors in S. cerevisiae upon treatment with HMF and furfural

2012

Common and Distant Structural Characteristics of Feruloyl Esterase Families from Aspergillus oryzae

HMF and furfural stress results in drainage of redox and energy charge of Saccharomyces cerevisiae

2012

The interplay between sulphur and selenium metabolism in yeast influences the intracellular redox balance

Biosynthesis of bioactive seleno-compounds in Saccharomyces cerevisiae

Descriptor-based computational analysis and molecular simulation studies reveals a novel classification scheme and structure-function relationship elements for feruloyl esterases

Biotechnology for production of bioactive seleno compounds and study of their influence on mouse metabolome

2011

Metabolic and Bioprocess Engineering for Production of selenized yeast with increased content of seleno-methylselenocysteine

Viability study of the use of cast iron open cell foam as microbial fuel cell electrodes.

Metabolism of selenium in Saccharomyces cerevisiae and improved biosynthesis of bioactive organic Se-compounds

Effects of selenium on Saccharomyces cerevisiae physiology: essential knowledge for the development of Se-enriched yeast cell factory

Biosyntheis of Bioactive Seleno-Compunds in Saccharomyces cerevisiae via Metabolic and Bioprocess Engineering

Metabolism of selenium in Saccharomyces cerevisiae and improved biosynthesis of bioactive organic Se-compounds

Biosynthesis of bioactive seleno-metabolites in Saccharomyces cerevisiae

Biosynthesis of bioactive seleno-metabolites in Saccharomyces cerevisiae

Metabolic footprinting in microbiology: methods and applications in functional genomics and biotechnology