Stefan Hohmann
Dr. Stefan Hohmann, born 1956-09-08, married, household of seven, four children (born 92, 94, 98, 00), one grand child (born 13) Study of Biology 1978-83, Ph.D. 1987, Habilitation 1993, Professor 2001 Research areas: • Yeast genetics, molecular biology, microbiology, systems biology • Signal transduction and stress responses • Structure-function analysis of transport proteins • Application of yeast in synthetic biology, biotechnology Professional appointments • Professor in Genetics and Head of Department, Chalmers University of Technology, 2015- • Professor in Molecular Microbial Physiology, University of Gothenburg, 2001-2015 • Declined: chair in Eukaryotic Microbiology, Uppsala University, 2000 • 1999-2005 research professor of the Swedish Research Council at University of Gothenburg • 1996-1999 temp. professor, University of Gothenburg and Chalmers University of Technology, Sweden • 1991, 1993 visiting professor at the University of the Orange Free State, South Africa • 1990-95 project leader at the Catholic University of Leuven, Belgium • 1986-90 post-doctoral researcher at the University of Darmstadt, Germany Scientific productivity • Ca 120 research papers in refereed journals and ca 25 review articles; H-index 45 • Editor of six scientific books/special issues and author of 21 book chapters • More than fifty invited contributions to national and international conferences • More than seventy lectures on invitation Teaching • Molecular microbiology, genetics, molecular biology, systems biology • Graduated 13 PhD students as supervisor • Out of ca 40 supervised PhD students and post-docs, eleven hold positions as full or associate professor Co-ordinator of five EC-funded research and development projects and of five international training projects. Organiser of the 3rd International Conference on Aquaporins (2000), the XXI International Conference on Yeast Genetics and Molecular Biology (2003 and again in 2019), the International Conference on Systems Biology (2008) and the 35th FEBS Congress (2010) Chief Editor of Molecular Genetics and Genomics (2005-), Current Genetics (2001-2014) and Topics in Current Genetics (2002-) Chairman of Häcksjön Science Publishing AB and board member Cereduce AB (previously Gothia Yeast Solutions AB)
Showing 132 publications
Applying microfluidic systems to study effects of glucose at single-cell level
Moving from Genetics to Systems Biology
The yeast osmostress response is carbon source dependent
Editor's comment on "CRISPR/Cas9-mediated gene editing in human zygotes using Cas9 protein"
Single-cell study links metabolism with nutrient signaling and reveals sources of variability
Transcription factor clusters regulate gene expression in yeast Saccharomyces cerevisiae
Transcription factor clusters regulate genes in eukaryotic cells
Single-Molecule Transcription Factor Dynamics in Saccharomyces Cerevisiae Glucose Sensing
3D millisecond tracking of single-molecule fluorescent protein translocation in eukaryotic cells
Strategies for structuring interdisciplinary education in systems biology: An European perspective
Systems Level Analysis of the Yeast Osmo-Stat
Molecular communication: crosstalk between the Snf1 and other signaling pathways
A fungicide-responsive kinase as a tool for synthetic cell fate regulation
An integrated view on a eukaryotic osmoregulation system
Bridging the gaps in systems biology
Yeast reveals unexpected roles and regulatory features of aquaporins and aquaglyceroporins.
Synthetic biology: lessons from engineering yeast MAPK signalling pathways.
Pheromone-Induced Morphogenesis Improves Osmoadaptation Capacity by Activating the HOG MAPK Pathway
Quantitative Analysis of Glycerol Accumulation, Glycolysis and Growth under Hyper Osmotic Stress
Yeast Aquaglyceroporins Use the Transmembrane Core to Restrict Glycerol Transport
A framework for mapping, visualisation and automatic model creation of signal-transduction networks.
Systems biology of microorganisms. Preface.
Distributed biological computation with multicellular engineered networks.
Quantification of cell volume changes upon hyperosmotic stress in Saccharomyces cerevisiae.
Gothenburg special issue: Molecules of life.
UNICELLSYS - Understanding the cell's functional organization
Saccharomyces cerevisiae Spore Germination
Functional analysis of the Ashbya gossypii Fps1 homolog
One hundred years of Molecular Genetics and Genomics: 100 years of extra-nuclear inheritance.
Control of high osmolarity signalling in the yeast Saccharomyces cerevisiae.
Systems Biology: Nobel Symposium 146.
Short cut to 1,2,3-triazole-based p38 MAP kinase inhibitors via [3+2]-cycloaddition chemistry
Crystal structure of a yeast aquaporin at 1.15 angstrom reveals a novel gating mechanism.
Robustness and fragility in the yeast High Osmolarity Glycerol (HOG) signal transduction pathway
Robustness and fragility in the high osmolarity glycerol (HOG) pathway in S. cerevisiae
Robustness and fragility in the yeast high osmolarity glycerol (HOG) signal-transduction pathway.
How quantitative measures unravel design principles in multi-stage phosphorylation cascades.
Expression of the yeast aquaporin AQY2 gene is negatively regulated via Hog1, Kss1, and Sfl1
Production, characterization and crystallization of the Plasmodium falciparum aquaporin.
Case study in systematic modelling: thiamine uptake in the yeast Saccharomyces cerevisiae.
Robustness and fragility in the yeast High Osmolarity signal transduction pathway
Robustness and fragility in the yeast High Osmolarity signal transduction pathway
Exploring the impact of osmoadaptation on glycolysis using time-varying response-coefficients
Revealing the secrets of dormancy and of survival during desiccation
Robustness analysis of HOG pathway related genes in budding yeast
Regulatory Mechanism of the Yeast Aquaporin AQY2 Expression Under Osmotic Condition.
Towards a structural and functional understanding of human aquaporin 9
Robustness analysis of HOG pathway related genes in Saccharomyces cerevisiae
Systembiologin kan förändra sjukvården radikalt
Structural and functional analysis of the osmoregulated yeast aquaglyceroporin Fps1.
Structural and functional analysis of the osmoregulated yeast aquaglyceroporin Fps1
Yeast systems biology to unravel the network of life
Genome-wide expression profile of the mnn2Δ mutant of Saccharomyces cerevisiae
Gis4, a new component of the ion homeostasis system in the yeast Saccharomyces cerevisiae
Pdc2 coordinates expression of the THI regulon in the yeast Saccharomyces cerevisiae
Role of Isc1p in oxidative stress resistance and ageing in yeast
Comparative analysis of HOG pathway proteins to generate hypotheses for functional analysis
Expression of heterologous aquaporins for functional analysis in Saccharomyces cerevisiae
Comparative genomics of the HOG-signalling system in fungi
A micro-fluidic system for studies of stress response in single cells using optical tweezers
Robustness analysis of HOG pathway genes in Saccharomyces cerevisiae
A simple mathematical model of adaptation to high osmolarity in yeast
Report of an EU Projects Workshop on Systems Biology held in Brussels, Belgium on 8 December 2004
Integrative model of the response of yeast to osmotic shock
Aquaporins in yeasts and filamentous fungi
Modelling signalling pathways-A yeast approach
Using yeast to study transport and structure-function relationship in aquaglyceroporins
The Yeast Systems Biology Network: mating communities
Role of Fps1 hydrophilic extensions and identification of residues controlling glycerol transport
Role of Fps1 hydrophilic extensions and identification of residues controlling glycerol transport
Analysis of the VPS74 gene of Saccharomyces cerevisiae using DNA microarrays
Turgor restoration: the critical event in signal cessation of the HOG pathway
A Regulatory Domain in the C-terminal Extension of the Yeast Glycerol Channel Fps1p
Shutting the MAP off - and on again?
Switching the mode of metabolism in the yeast Saccharomyces cerevisiae.
The Saccharomyces cerevisiae aquaporin Aqy1 is involved in sporulation
Role of hexose transport in control of glycolytic flux in Saccharomyces cerevisiae
Transcriptional responses to glucose at different glycolytic rates in Saccharomyces cerevisiae
Anaerobicity prepares Saccharomyces cerevisiae cells for faster adaptation to osmotic shock
Downregulation of the HOG MAP kinase pathway during yeast osmoadaptation
A Short Regulatory Domain Restricts Glycerol Transport through Yeast Fps1p
A short regulatory domain restricts glycerol transport through yeast Fps1p
Gis4p is a novel component of ion homeostasis in the yeast Saccharomyces cerevisiae
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Showing 3 research projects
Synthetic Circuits for Robust Orthogonal Production (SynCrop)
Integration av metabolism och signalöverföring: den AMP-aktivierade protein kinas SNF1 i jäst