Scott Mazurkewich

Researcher at Industrial Biotechnology

Scott Mazurkewich joined the Division of Industrial Biotechnology in August 2016 as a postdoctoral researcher. He is investigating enzymes from strains of Bacteroidetes, strains which are known to degrade hemicellulose from a wide array of plant sources. The aim of project, which is supported by the Wallenberg Wood Science Center (WWSC), is to advance our knowledge about these important enzymes for the development of novel biomass utilization methods.

Source: chalmers.se

Contact Details ORCID

Publications (22)
Projects (2)

Showing 22 publications

2024

Polysaccharide utilization loci from Bacteroidota encode CE15 enzymes with possible roles in cleaving pectin-lignin bonds

Andrea Seveso, Scott Mazurkewich, Sanchari Banerjee et al

Applied and Environmental Microbiology. Vol. 90 (1)

Journal article

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2023

Structural and functional investigation of a fungal member of carbohydrate esterase family 15 with potential specificity for rare xylans

Scott Mazurkewich, Karoline Scholzen, Rikke Brusch et al

Acta Crystallographica Section D: Structural Biology. Vol. 79, p. 545-555

Journal article

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2023

A unique AA5 alcohol oxidase fused with a catalytically inactive CE3 domain from the bacterium Burkholderia pseudomallei

Scott Mazurkewich, Andrea Seveso, Johan Larsbrink

FEBS Letters. Vol. 597 (13), p. 1779-1791

Journal article

2022

Characterization of three tannases from Clostridium butyricum active on oak bark extract

Amanda Sörensen Ristinmaa, Johan Larsbrink, Scott Mazurkewich et al

Other conference contribution

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2022

Mechanism of the glucuronoyl esterase OtCE15A: an alpha/beta hydrolase involved with biomass conversion

Scott Mazurkewich, Zhiyou Zong, Haohao Fu et al

Conference poster

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2022

Structural diversity and substrate preferences of three tannase enzymes encoded by the anaerobic bacterium Clostridium butyricum

Amanda Sörensen Ristinmaa, Tom Coleman, Leona Cesar et al

Journal of Biological Chemistry. Vol. 298 (4)

Journal article

2022

Enzymes targeting lignin-carbohydrate complexes

Andrea Seveso, Scott Mazurkewich, Johan Larsbrink

Conference poster

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2022

Mechanism and biomass association of glucuronoyl esterase: an α/β hydrolase with potential in biomass conversion

Zhiyou Zong, Scott Mazurkewich, Caroline Pereira et al

Nature Communications. Vol. 13 (1)

Journal article

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2021

Characterization of a novel multidomain CE15-GH8 enzyme encoded by a polysaccharide utilization locus in the human gut bacterium Bacteroides eggerthii

Cathleen Kmezik, Daniel Krska, Scott Mazurkewich et al

Scientific Reports. Vol. 11 (1)

Journal article

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2021

Structure of a C1/C4-oxidizing AA9 lytic polysaccharide monooxygenase from the thermophilic fungus Malbranchea cinnamomea

Scott Mazurkewich, Andrea Seveso, Silvia Hüttner et al

Acta Crystallographica Section D: Structural Biology. Vol. 77, p. 1019-1026

Journal article

2021

A polysaccharide utilization locus from the gut bacterium dysgonomonas mossii encodes functionally distinct carbohydrate esterases

Cathleen Kmezik, Scott Mazurkewich, Tomke Meents et al

Journal of Biological Chemistry. Vol. 296

Journal article

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2021

Biochemical characterization of three tannases from Clostridium butyricum

Amanda Sörensen Ristinmaa, Tom Coleman, Leona Cesar et al

Conference poster

2021

Structural and Functional Analysis of a Multimodular Hyperthermostable Xylanase-Glucuronoyl Esterase from Caldicellulosiruptor kristjansonii

Daniel Krska, Scott Mazurkewich, Haley A. Brown et al

Biochemistry. Vol. 60 (27), p. 2206-2220

Journal article

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2020

Structural insights of the enzymes from the chitin utilization locus of Flavobacterium johnsoniae

Scott Mazurkewich, Ronny Helland, Alasdair Mackenzie et al

Scientific Reports. Vol. 10 (1)

Journal article

2020

Genomic and transcriptomic analysis of Candida intermedia reveals the genetic determinants for its xylose-converting capacity

Cecilia Geijer, Fábio Luis Da Silva Faria Oliveira, David Moreno et al

Biotechnology for Biofuels. Vol. 13 (1)

Journal article

2020

Multimodular fused acetyl–feruloyl esterases from soil and gut Bacteroidetes improve xylanase depolymerization of recalcitrant biomass

Cathleen Kmezik, Cyrielle Bonzom, Lisbeth Olsson et al

Biotechnology for Biofuels. Vol. 13 (1)

Journal article

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2019

Structural and biochemical studies of the glucuronoyl esterase OtCE15A illuminate its interaction with lignocellulosic components

Scott Mazurkewich, Jens-Christian N Poulsen, Leila Lo Leggio et al

Journal of Biological Chemistry. Vol. 294 (52), p. 19978-19987

Journal article

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2019

ACTIVE SITE EVOLUTION IN BIOMASS DEGRADING ENZYMES

Kristian E. H. Frandsen, Tobias Tandrup, Jens-Christian N. Poulsen et al

Other conference contribution

2019

Structure-function analyses reveal that a glucuronoyl esterase from Teredinibacter turnerae interacts with carbohydrates and aromatic compounds

Jenny Arnling Bååth, Scott Mazurkewich, J. C. N. Poulsen et al

Journal of Biological Chemistry. Vol. 294 (16), p. 6635-6644

Journal article

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2019

Understanding enzyme-substrate interactions in Carbohydrate Esterase Family 15

Scott Mazurkewich, Jenny Arnling Bååth, Jens-Christian N Poulsen et al

Conference poster

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2018

Biochemical and structural features of diverse bacterial glucuronoyl esterases facilitating recalcitrant biomass conversion

Jenny Arnling Bååth, Scott Mazurkewich, Rasmus Meland Knudsen et al

Biotechnology for Biofuels. Vol. 11 (1)

Journal article

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2018

Biochemical and structural investigation of the CE15 family: Glucuronoyl esterases acting on recalcitrant biomass

Scott Mazurkewich, Jenny Arnling Bååth, Rasmus Meland Knudsen et al

Conference poster

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Showing 2 research projects

2021–2024

Terahertz Technology for Probing Picosecond Protein Dynamics under Physiological Conditions

Helena Rodilla Terahertz and Millimetre Wave Laboratory

Johan Larsbrink Industrial Biotechnology

Scott Mazurkewich Industrial Biotechnology

Juan Cabello Sánchez Terahertz and Millimetre Wave Laboratory

Swedish Research Council (VR)

2016–2021

Structure-function studies of enzymes cleaving covalent bonds between lignin and hemicelluloses

Daniel Krska Industrial Biotechnology

Scott Mazurkewich Industrial Biotechnology

Johan Larsbrink Industrial Biotechnology

Andrea Seveso Industrial Biotechnology

Novo Nordisk Foundation

Interreg

6 publications exist

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