Scott Mazurkewich

Researcher at Industrial Biotechnology

Scott Mazurkewich joined the Division of Industrial Biotechnology in August 2016 as a postdoctoral researcher. He is investigating enzymes from strains of Bacteroidetes, strains which are known to degrade hemicellulose from a wide array of plant sources. The aim of project, which is supported by the Wallenberg Wood Science Center (WWSC), is to advance our knowledge about these important enzymes for the development of novel biomass utilization methods.

Source: chalmers.se
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Showing 27 publications

2024

Genomic mining of <i>Geobacillus stearothermophilus</i> GF16 for xylose production from hemicellulose-rich biomasses using secreted enzymes

M. Carbonaro, M. Aulitto, A. Di Fraia et al
FEBS Open Bio. Vol. 14 (S2), p. 148-149
Other text in scientific journal
2024

Polysaccharide utilization loci from Bacteroidota encode CE15 enzymes with possible roles in cleaving pectin-lignin bonds

Andrea Seveso, Scott Mazurkewich, Sanchari Banerjee et al
Applied and Environmental Microbiology. Vol. 90 (1)
Journal article
2024

Exploration of three Dyadobacter fermentans enzymes uncovers molecular activity determinants in CE15

Miriam Carbonaro, Scott Mazurkewich, Gabriella Fiorentino et al
Applied Microbiology and Biotechnology. Vol. 108 (1)
Journal article
2024

Structural and biochemical analysis of family 92 carbohydrate-binding modules uncovers multivalent binding to β-glucans

Meng Shu Hao, Scott Mazurkewich, He Li et al
Nature Communications. Vol. 15 (1)
Journal article
2024

Boosting Enzyme Activity in Biomass Conversion by Modulating the Hydrolysis Process of Cellobiohydrolases

Han Liu, Yu Ding, Scott Mazurkewich et al
ACS Catalysis, p. 16044-16054
Journal article
2024

Genomic mining of Geobacillus stearothermophilus GF16 for xylose production from hemicellulose-rich biomasses using secreted enzymes

Miriam Carbonaro, Martina Aulitto, Scott Mazurkewich et al
New Biotechnology. Vol. 82, p. 14-24
Journal article
2023

Structural and functional investigation of a fungal member of carbohydrate esterase family 15 with potential specificity for rare xylans

Scott Mazurkewich, Karoline Scholzen, Rikke Brusch et al
Acta Crystallographica Section D: Structural Biology. Vol. 79, p. 545-555
Journal article
2023

A unique AA5 alcohol oxidase fused with a catalytically inactive CE3 domain from the bacterium Burkholderia pseudomallei

Scott Mazurkewich, Andrea Seveso, Johan Larsbrink
FEBS Letters. Vol. 597 (13), p. 1779-1791
Journal article
2022

Characterization of three tannases from Clostridium butyricum active on oak bark extract

Amanda Sörensen Ristinmaa, Johan Larsbrink, Scott Mazurkewich et al
Other conference contribution
2022

Structural diversity and substrate preferences of three tannase enzymes encoded by the anaerobic bacterium Clostridium butyricum

Amanda Sörensen Ristinmaa, Tom Coleman, Leona Cesar et al
Journal of Biological Chemistry. Vol. 298 (4)
Journal article
2022

Enzymes targeting lignin-carbohydrate complexes

Andrea Seveso, Scott Mazurkewich, Johan Larsbrink
Conference poster
2022

Mechanism and biomass association of glucuronoyl esterase: an α/β hydrolase with potential in biomass conversion

Zhiyou Zong, Scott Mazurkewich, Caroline Pereira et al
Nature Communications. Vol. 13 (1)
Journal article
2021

Structure of a C1/C4-oxidizing AA9 lytic polysaccharide monooxygenase from the thermophilic fungus Malbranchea cinnamomea

Scott Mazurkewich, Andrea Seveso, Silvia Hüttner et al
Acta Crystallographica Section D: Structural Biology. Vol. 77, p. 1019-1026
Journal article
2021

A polysaccharide utilization locus from the gut bacterium dysgonomonas mossii encodes functionally distinct carbohydrate esterases

Cathleen Kmezik, Scott Mazurkewich, Tomke Meents et al
Journal of Biological Chemistry. Vol. 296
Journal article
2021

Biochemical characterization of three tannases from Clostridium butyricum

Amanda Sörensen Ristinmaa, Tom Coleman, Leona Cesar et al
Conference poster
2021

Structural and Functional Analysis of a Multimodular Hyperthermostable Xylanase-Glucuronoyl Esterase from Caldicellulosiruptor kristjansonii

Daniel Krska, Scott Mazurkewich, Haley A. Brown et al
Biochemistry. Vol. 60 (27), p. 2206-2220
Journal article
2020

Structural insights of the enzymes from the chitin utilization locus of Flavobacterium johnsoniae

Scott Mazurkewich, Ronny Helland, Alasdair Mackenzie et al
Scientific Reports. Vol. 10 (1)
Journal article
2020

Genomic and transcriptomic analysis of Candida intermedia reveals the genetic determinants for its xylose-converting capacity

Cecilia Geijer, Fábio Luis Da Silva Faria Oliveira, David Moreno et al
Biotechnology for Biofuels. Vol. 13 (1)
Journal article
2020

Multimodular fused acetyl–feruloyl esterases from soil and gut Bacteroidetes improve xylanase depolymerization of recalcitrant biomass

Cathleen Kmezik, Cyrielle Bonzom, Lisbeth Olsson et al
Biotechnology for Biofuels. Vol. 13 (1)
Journal article
2019

Structural and biochemical studies of the glucuronoyl esterase OtCE15A illuminate its interaction with lignocellulosic components

Scott Mazurkewich, Jens-Christian N Poulsen, Leila Lo Leggio et al
Journal of Biological Chemistry. Vol. 294 (52), p. 19978-19987
Journal article
2019

ACTIVE SITE EVOLUTION IN BIOMASS DEGRADING ENZYMES

Kristian E. H. Frandsen, Tobias Tandrup, Jens-Christian N. Poulsen et al
Other conference contribution
2019

Structure-function analyses reveal that a glucuronoyl esterase from Teredinibacter turnerae interacts with carbohydrates and aromatic compounds

Jenny Arnling Bååth, Scott Mazurkewich, J. C. N. Poulsen et al
Journal of Biological Chemistry. Vol. 294 (16), p. 6635-6644
Journal article
2019

Understanding enzyme-substrate interactions in Carbohydrate Esterase Family 15

Scott Mazurkewich, Jenny Arnling Bååth, Jens-Christian N Poulsen et al
Conference poster
2018

Biochemical and structural features of diverse bacterial glucuronoyl esterases facilitating recalcitrant biomass conversion

Jenny Arnling Bååth, Scott Mazurkewich, Rasmus Meland Knudsen et al
Biotechnology for Biofuels. Vol. 11 (1)
Journal article
2018

Biochemical and structural investigation of the CE15 family: Glucuronoyl esterases acting on recalcitrant biomass

Scott Mazurkewich, Jenny Arnling Bååth, Rasmus Meland Knudsen et al
Conference poster

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Showing 2 research projects

2021–2025

Terahertz Technology for Probing Picosecond Protein Dynamics under Physiological Conditions

Helena Rodilla Terahertz and Millimetre Wave Laboratory
Johan Larsbrink Industrial Biotechnology
Scott Mazurkewich Industrial Biotechnology
Juan Cabello Sánchez Terahertz and Millimetre Wave Laboratory
Swedish Research Council (VR)

2016–2021

Structure-function studies of enzymes cleaving covalent bonds between lignin and hemicelluloses

Daniel Krska Industrial Biotechnology
Scott Mazurkewich Industrial Biotechnology
Johan Larsbrink Industrial Biotechnology
Andrea Seveso Industrial Biotechnology
Novo Nordisk Foundation
Interreg

6 publications exist
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