Eduard Kerkhoven

Senior forskare vid Systembiologi

Eduard tillhör gruppen systembiologi. Se den engelska sidan för mer information.

Källa: chalmers.se
Image of Eduard Kerkhoven

Visar 47 publikationer

2022

Urea is a drop-in nitrogen source alternative to ammonium sulphate in Yarrowia lipolytica

Oliver Konzock, Simone Zaghen, Jing Fu et al
iScience. Vol. 25 (12)
Artikel i vetenskaplig tidskrift
2022

Deep learning-based k(cat) prediction enables improved enzyme-constrained model reconstruction

Feiran Li, Le Yuan, Hongzhong Lu et al
NATURE CATALYSIS. Vol. In Press
Artikel i vetenskaplig tidskrift
2022

A Pan-Draft Metabolic Model Reflects Evolutionary Diversity across 332 Yeast Species

Hongzhong Lu, Eduard Kerkhoven, Jens B Nielsen
Biomolecules. Vol. 12 (11)
Artikel i vetenskaplig tidskrift
2022

Advances in constraint-based models: methods for improved predictive power based on resource allocation constraints

Eduard Kerkhoven
Current Opinion in Microbiology. Vol. 68
Reviewartikel
2022

Reconstruction of Genome-Scale Metabolic Model for Hansenula polymorpha Using RAVEN

Francisco Zorrilla, Eduard Kerkhoven
Methods in Molecular Biology, p. 271-290
Kapitel i bok
2022

Genome-scale metabolic model of oleaginous yeast Papiliotrema laurentii

Rafaela Zandonade Ventorim, Maurício Alexander de Moura Ferreira, Eduardo Luís Menezes de Almeida et al
Biochemical Engineering Journal. Vol. 180
Artikel i vetenskaplig tidskrift
2022

Validated Growth Rate-Dependent Regulation of Lipid Metabolism in Yarrowia lipolytica

Naghmeh Poorinmohammad, Jing Fu, Bob Wabeke et al
International Journal of Molecular Sciences. Vol. 23 (15)
Artikel i vetenskaplig tidskrift
2022

Reconstruction of a catalogue of genome-scale metabolic models with enzymatic constraints using GECKO 2.0

Iván Domenzain Del Castillo Cerecer, Benjamín José Sánchez, Petre Mihail Anton et al
Nature Communications. Vol. 13 (1)
Artikel i vetenskaplig tidskrift
2022

Generation and analysis of context-specific genome-scale metabolic models derived from single-cell RNA-Seq data

Johan Gustafsson, Jonathan Robinson, Fariba Roshanzamir et al
Preprint
2022

Improving recombinant protein production by yeast through genome-scale modeling using proteome constraints

Feiran Li, Yu Chen, Qi Qi et al
Nature Communications. Vol. 13 (1)
Artikel i vetenskaplig tidskrift
2022

Multiscale models quantifying yeast physiology: towards a whole-cell model

Hongzhong Lu, Eduard Kerkhoven, Jens B Nielsen
Trends in Biotechnology. Vol. 40 (3), p. 291-305
Reviewartikel
2021

Systems-level approaches for understanding and engineering of the oleaginous cell factory Yarrowia lipolytica

Naghmeh Poorinmohammad, Eduard Kerkhoven
Biotechnology and Bioengineering. Vol. 118 (10), p. 3640-3654
Reviewartikel
2021

Editorial: Multi-Omics Technologies for Optimizing Synthetic Biomanufacturing

Young Mo Kim, Christopher J. Petzold, Eduard Kerkhoven et al
Frontiers in Bioengineering and Biotechnology. Vol. 9
Övrig text i vetenskaplig tidskrift
2021

Adaptations in metabolism and protein translation give rise to the Crabtree effect in yeast

Carl Malina, Rosemary Brown, Johan Björkeroth et al
Proceedings of the National Academy of Sciences of the United States of America. Vol. 118 (51)
Artikel i vetenskaplig tidskrift
2021

Reconstruction of a Genome-Scale Metabolic Model of Streptomyces albus J1074: Improved Engineering Strategies in Natural Product Synthesis

Cheewin Kittikunapong, Suhui Ye, Patricia Magadan-Corpas et al
Metabolites. Vol. 11 (5)
Artikel i vetenskaplig tidskrift
2021

Evaluating accessibility, usability and interoperability of genome-scale metabolic models for diverse yeasts species

Iván Domenzain Del Castillo Cerecer, Feiran Li, Eduard Kerkhoven et al
FEMS Yeast Research. Vol. 21 (1)
Reviewartikel
2021

Constraint-based modeling of yeast mitochondria reveals the dynamics of protein import and iron-sulfur cluster biogenesis

Carl Malina, Francesca Di Bartolomeo, Eduard Kerkhoven et al
ISCIENCE. Vol. 24 (11)
Artikel i vetenskaplig tidskrift
2021

The yeastGemMap: A process diagram to assist yeast systems-metabolic studies

Luis Caspeta-Guadarrama, Eduard Kerkhoven, Alfredo Martinez et al
Biotechnology and Bioengineering. Vol. 118 (12), p. 4800-4814
Artikel i vetenskaplig tidskrift
2021

Yeast metabolic innovations emerged via expanded metabolic network and gene positive selection

Hongzhong Lu, Feiran Li, Le Yuan et al
Molecular Systems Biology. Vol. 17 (10)
Artikel i vetenskaplig tidskrift
2020

An atlas of human metabolism

Jonathan Robinson, Pinar Kocabas, Hao Wang et al
Science signaling. Vol. 13 (624)
Artikel i vetenskaplig tidskrift
2020

Nitrogen as the major factor influencing gene expression in Yarrowia lipolytica

Piotr Hapeta, Eduard Kerkhoven, Zbigniew Lazar
Biotechnology Reports. Vol. 27
Artikel i vetenskaplig tidskrift
2020

C/N ratio and carbon source-dependent lipid production profiling in Rhodotorula toruloides

Helberth Júnnior Santos Lopes, Nemailla Bonturi, Eduard Kerkhoven et al
Applied Microbiology and Biotechnology. Vol. 104 (6), p. 2639-2649
Artikel i vetenskaplig tidskrift
2020

Extracting novel hypotheses and findings from RNA-seq data

Tyler Doughty, Eduard Kerkhoven
FEMS Yeast Research. Vol. 20 (2)
Reviewartikel
2020

Enzyme-Constrained Models and Omics Analysis of Streptomyces coelicolor Reveal Metabolic Changes that Enhance Heterologous Production

Snorre Sulheim, Tjaša Kumelj, Dino van Dissel et al
iScience. Vol. 23 (9)
Artikel i vetenskaplig tidskrift
2019

Proteome analysis of xylose metabolism in Rhodotorula toruloides during lipid production

Ievgeniia Tiukova, Jule Brandenburg, Johanna Blomqvist et al
Biotechnology for Biofuels. Vol. 12 (1)
Artikel i vetenskaplig tidskrift
2019

A consensus S. cerevisiae metabolic model Yeast8 and its ecosystem for comprehensively probing cellular metabolism

Hongzhong Lu, Feiran Li, Benjamín José Sánchez et al
Nature Communications. Vol. 10 (1)
Artikel i vetenskaplig tidskrift
2019

SLIMEr: Probing flexibility of lipid metabolism in yeast with an improved constraint-based modeling framework

Benjamín José Sánchez, Feiran Li, Eduard Kerkhoven et al
BMC Systems Biology. Vol. 13 (1)
Artikel i vetenskaplig tidskrift
2019

Investigating the Influence of Glycerol on the Utilization of Glucose in Yarrowia lipolytica Using RNA-Seq-Based Transcriptomics

Patrice Lubuta, M. Workman, Eduard Kerkhoven et al
G3: Genes, Genomes, Genetics. Vol. 9 (12), p. 4059-4071
Artikel i vetenskaplig tidskrift
2019

Mapping the metabolism of five amino acids in bloodstream form Trypanosoma brucei using U- 13C-labelled substrates and LC–MS

Katharina Johnston, D. H. Kim, Eduard Kerkhoven et al
Bioscience Reports. Vol. 39 (5)
Artikel i vetenskaplig tidskrift
2019

Genome-scale model of Rhodotorula toruloides metabolism

Ievgeniia Tiukova, Sylvain Prigent, Jens B Nielsen et al
Biotechnology and Bioengineering. Vol. 116 (12), p. 3396-3408
Artikel i vetenskaplig tidskrift
2018

Regulation of yeast-to-hyphae transition in Yarrowia lipolytica

Kyle R. Pomraning, Erin L. Bredeweg, Eduard Kerkhoven et al
mSphere. Vol. 3 (6)
Artikel i vetenskaplig tidskrift
2018

RAVEN 2.0: A versatile toolbox for metabolic network reconstruction and a case study on Streptomyces coelicolor

Hao Wang, Simonas Marcisauskas, Benjamin José Sanchez Barja et al
PLoS Computational Biology. Vol. 14 (10), p. e1006541-
Artikel i vetenskaplig tidskrift
2018

Barriers and opportunities in bio-based production of hydrocarbons

Yongjin Zhou, Eduard Kerkhoven, Jens B Nielsen
Nature Energy. Vol. 3 (11), p. 925-935
Reviewartikel
2018

Advancing metabolic engineering of Yarrowia lipolytica using the CRISPR/Cas system

Tian Qiong Shi, He Huang, Eduard Kerkhoven et al
Applied Microbiology and Biotechnology. Vol. 102 (22), p. 9541-9548
Reviewartikel
2017

A molecular genetic toolbox for Yarrowia lipolytica

Erin L. Bredeweg, Kyle R. Pomraning, Ziyu Dai et al
Biotechnology for Biofuels. Vol. 10 (1)
Artikel i vetenskaplig tidskrift
2017

Leucine Biosynthesis Is Involved in Regulating High Lipid Accumulation in Yarrowia lipolytica

Eduard Kerkhoven, Y. M. Kim, S. W. Wei et al
mBio. Vol. 8 (3), p. Article no. e00857-17
Artikel i vetenskaplig tidskrift
2017

Improving the phenotype predictions of a yeast genome-scale metabolic model by incorporating enzymatic constraints

Benjamin José Sanchez Barja, C. Zhang, Avlant Nilsson et al
Molecular Systems Biology. Vol. 13 (8), p. Article no 935 -
Artikel i vetenskaplig tidskrift
2016

Regulation of amino-acid metabolism controls flux to lipid accumulation in yarrowia lipolytica

Eduard Kerkhoven, Kyle R. Pomraning, S. E. Baker et al
npj Systems Biology and Applications. Vol. 2
Artikel i vetenskaplig tidskrift
2016

Genome-scale metabolic model of Pichia pastoris with native and humanized glycosylation of recombinant proteins

Z. A. Irani, Eduard Kerkhoven, S. A. Shojaosadati et al
Biotechnology and Bioengineering. Vol. 113 (5), p. 961-969
Artikel i vetenskaplig tidskrift
2015

Probing the Metabolic Network in Bloodstream-Form Trypanosoma brucei Using Untargeted Metabolomics with Stable Isotope Labelled Glucose

D. J. Creek, M. Mazet, F. Achcar et al
PLoS Pathogens. Vol. 11 (3), p. 1-25
Artikel i vetenskaplig tidskrift
2015

Applications of computational modeling in metabolic engineering of yeast

Eduard Kerkhoven, Petri-Jaan Lahtvee, Jens B Nielsen
FEMS Yeast Research. Vol. 15 (1)
Artikel i vetenskaplig tidskrift
2015

TrypanoCyc: a community-led biochemical pathways database for Trypanosoma brucei

S. Shameer, F. J. Logan-Klumpler, F. Vinson et al
Nucleic Acids Research. Vol. 43 (D1), p. D637-D644
Artikel i vetenskaplig tidskrift
2015

Crystal Structure of an Arginase-like Protein from Trypanosoma brucei That Evolved without a Binuclear Manganese Cluster

Y. Hai, Eduard Kerkhoven, M. P. Barrett et al
Biochemistry. Vol. 54 (2), p. 458-471
Artikel i vetenskaplig tidskrift
2014

The Silicon Trypanosome: A Test Case of Iterative Model Extension in Systems Biology

F. Achcar, A. Fadda, J. R. Haanstra et al
Advances in Microbial Physiology. Vol. 64, p. 115-143
Kapitel i bok
2014

Trypanosoma brucei: meet the system

F. Achcar, Eduard Kerkhoven, M. P. Barrett
Current Opinion in Microbiology. Vol. 20, p. 162-169
Reviewartikel
2014

Genome Scale Metabolic Modeling of the Riboflavin Overproducer Ashbya gossypii

R. Ledesma-Amaro, Eduard Kerkhoven, J. L. Revuelta et al
Biotechnology and Bioengineering. Vol. 111 (6), p. 1191-1199
Artikel i vetenskaplig tidskrift
2013

Handling Uncertainty in Dynamic Models: The Pentose Phosphate Pathway in Trypanosoma brucei

Eduard Kerkhoven, F. Achcar, V. P. Alibu et al
PLoS Computational Biology. Vol. 9 (12), p. Art. no. e1003371-
Artikel i vetenskaplig tidskrift

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Visar 5 forskningsprojekt

2019–2023

Uppvaknande av kryptiska biosyntetiska genkluster med fet röd jäst

Eduard Kerkhoven Systembiologi
Vetenskapsrådet (VR)

1 publikation finns
2019–2021

Optimera mikrobiell tillverkning av itakonat för hållbar plast och tvättmedel

Eduard Kerkhoven Systembiologi
Formas

2 publikationer finns
2018–

Engineering a robust biocatalyst for sustainable biofuel production

Eduard Kerkhoven Systembiologi
Jens B Nielsen Systembiologi
Chalmers

2016–2018

From electricity towards biodiesel production in yeast

Eduard Kerkhoven Systembiologi
ÅForsk

2015–2018

Systematic Rebuilding of Actinomycetes for Natural Product Formation (ERASysAPP - SYSTERACT)

Eduard Kerkhoven Systembiologi
Västra Götalandsregionen

1 publikation finns
Det kan finnas fler projekt där Eduard Kerkhoven medverkar, men du måste vara inloggad som anställd på Chalmers för att kunna se dem.