Carl Johan Franzén

2023

Novel Insights into the Molecular Mechanisms Underlying Robustness and Stability in Probiotic Bifidobacteria

2022

Stress Response in Bifidobacteria

2022

Genome-Wide Assessment of Stress-Associated Genes in Bifidobacteria

2021

Identifying the essential nutritional requirements of the probiotic bacteria Bifidobacterium animalis and Bifidobacterium longum through genome-scale modeling

2021

Analysis of methods for quantifying yeast cell concentration in complex lignocellulosic fermentation processes

Why are you stressed? A systems-level comparison of two Bifidobacterium strains with different stability characteristics

2020

Multi-Scale Variability Analysis of Wheat Straw-Based Ethanol Biorefineries Identifies Bioprocess Designs Robust Against Process Input Variations

2020

Respiratory Physiology of Lactococcus lactis in Chemostat Cultures and Its Effect on Cellular Robustness in Frozen and Freeze-Dried Starter Cultures

2019

Presence of galactose in precultures induces lacS and leads to short lag phase in lactose-grown Lactococcus lactis cultures

2019

Seed culture pre-adaptation of Bacillus coagulans MA-13 improves lactic acid production in simultaneous saccharification and fermentation

2019

Draft genome sequence of bacillus coagulans ma-13, a thermophilic lactic acid producer from lignocellulose

2018

A novel chimaeric flocculation protein enhances flocculation in Saccharomyces cerevisiae

Multi-scale uncertainty analysis – A tool to systematically consider variability in lignocellulosic bioethanol processes

Uncertainty analysis as a tool to consistently evaluate lignocellulosic bioethanol processes at different system scales

Multi-feed simultaneous saccharification and fermentation: model-based development of high gravity lignocellulose-based bioprocesses

2017

Bacillus coagulans MA-13: a promising thermophilic and cellulolytic strain for the production of lactic acid from lignocellulosic hydrolysate

Modelling and uncertainty assessment for Simultaneous Saccharification and Co-Fermentation (SSCF) processes

2017

Saccharomyces cerevisiae strain comparison in glucose-xylose fermentations on defined substrates and in high-gravity SSCF: convergence in strain performance despite differences in genetic and evolutionary engineering history

2017

Sustaining fermentation in high-gravity ethanol production by feeding yeast to a temperature-profiled multifeed simultaneous saccharification and co-fermentation of wheat straw

High gravity lignocellulose bioprocess development for ethanol and lactic acid production by multi-feed simultaneous saccharification and fermentation

Water management in lignocellulosic ethanol production - A case study and comparative analysis from a Swedish perspective

Inlärning av tröskelbegreppen inom Bioreaktionsteknik - studentdriven utveckling av en webbaserad modul för självstudier

Which methods for viable yeast cell quantification can be used in lignocellulosic fermentation processes

Water Management in Lignocellulosic Ethanol Production- a Case Study and Comparative Analysis from a Swedish Perspective

2016

Model-based optimization and scale-up of multi-feed simultaneous saccharification and co-fermentation of steam pre-treated lignocellulose enables high gravity ethanol production.

Characterization of the respiratory physiology of Lactococcus lactis for starter culture production with improved acidification capacity

Dynamic flux balancing elucidates NAD(P)H production as limiting response to furfural inhibition in Saccharomyces cerevisiae

Factors affecting the viability of Saccharomyces cerevisiae in Simultaneous Saccharification and co-Fermentation of pretreated wheat straw to ethanol

Scale-up of multi feed fed-batch simultaneous saccharification and co-fermentation of pretreated wheat straw to ethanol

Kinetic modeling-based optimization of multi-feed simultaneous saccharification and co-fermentation of wheat straw for ethanol production

Multifeed simultaneous saccharification and fermentation enables high gravity submerged fermentation of lignocellulose.

What induces respiration in lactic acid bacteria? Characterization of respiratory metabolism of Lactococcus lactis in bioreactors for production of starter cultures with improved acidification capacity

2015

Current progress in high cell density yeast bioprocesses for bioethanol production

A FLO1 variant which yields a NewFlo phenotype

Flocculation Causes Inhibitor Tolerance in Saccharomyces cerevisiae for Second-Generation Bioethanol Production

Process optimization of multi-feed SSCF

2014

Improved sugar co-utilisation by encapsulation of a recombinant Saccharomyces cerevisiae strain in alginate-chitosan capsules

Kinetic modeling of multi-feed simultaneous saccharification and co-fermentation of pretreated birch to ethanol

2014

Continuous ethanol production with a membrane bioreactor at high acetic acid concentrations

Improved fermentation of inhibitory lignocellulose hydrolysates by Saccharomyces cerevisiae at high local cell density

Novel process strategies lead towards efficient bioethanol production at high solid loadings

Improved inhibitor tolerance and simultaneous utilisation of hexoses and pentoses during fermentation of inhibitory lignocellulose hydrolysates by yeast at high local cell density

High local cell density for efficient 2nd generation bioethanol production by Saccharomyces cerevisiae

Systems biology methods and developments for Saccharomyces cerevisiae and other industrial yeasts in relation to the production of fermented food and food ingredients

2013

Impact of Furfural on Rapid Ethanol Production Using a Membrane Bioreactor

Mechanically robust polysiloxane – ACA capsules for prolonged ethanol production

Rapid ethanol production by Saccharomyces cerevisiae in a membrane bioreactor

Together we are strong – Yeast flocculation for efficient fermentation of toxic hydrolysates

A novel process configuration of Simultaneous Saccharification and Fermentation for bioethanol production at high solid loadings

2012

Encapsulation-Induced Stress Helps Saccharomyces cerevisiae Resist Convertible Lignocellulose Derived Inhibitors

Inhibitor tolerance by high local cell density Saccharomyces cerevisiae cultures

Effects of encapsulation of microorganisms on product formation during microbial fermentations

Investigations of the inhibitor tolerance of encapsulated Saccharomyces cerevisiae

Physiological consequences of encapsulating Saccharomyces cerevisiae: A proteomic approach

2012

Proteomic analysis of the increased stress tolerance of Saccharomyces cerevisiae encapsulated in liquid core alginate-chitosan capsules

A novel process configuration of Simultaneous Saccharification and Fermentation for bioethanol production at high solid loadings

2012

Inhibitor tolerance and flocculation of a yeast strain suitable for second generation bioethanol production

2012

Robust liquid core APTES-alginate-chitosan-alginate capsules for 2nd generation bioethanol production

Physiological consequenses of high local cell density Saccharomyces cerevisiae cultures

Physiological consequences of encapsulating Saccharomyces cerevisiae: A proteomic approach

2012

Robust polysiloxane-ACA capsules for ethanol production from wood hydrolyzate by yeast

A novel process configuration of simultaneous saccharification and fermentation for bioethanol production at high solid loadings

Encapsulated vs. free yeast: A comparative proteomic study

2011

Selective suppression of bacterial contaminants by process conditions during lignocellulose based yeast fermentations

Ethanol production at elevated temperatures using encapsulation of yeast

Inhibitor tolerance and flocculation: Characterization of a yeast strain suitable for 2nd generation bioethanol production

Encapsulation of yeast for efficient 2nd generation bioethanol production: Finite element modeling of concentration profiles in encapsulated yeast

THERMOTOLERANCE OF ENCAPSULATED YEAST

Increasing the thermotolerance of Saccharomyces cerevisiae by encapsulation

Phenotypical and Physiological Characterization of a Flocculating Yeast Strain

Improving the stability and mechanical resistance of chitosan/alginate capsules for encapsulation of S. cerevisiae

On-line monitoring of fermentation processes in lignocellulose-to-bioalcohol production.

Together we are strong! Inhibitor tolerance conferred by good neighbors?

Ethanol production from lignocellulosic materials by encapsulated Saccharomyces cerevisiae

Characterization of glucose transport mutants of saccharomyces cerevisiae during a nutritional upshift reveals a correlation between metabolite levels and glycolytic flux

Conservation laws and identifiability of rate expressions in biochemical models

Continuous fermentation of wheat-supplemented lignocellulose hydrolysate with different types of cell retention

The impact of severe nitrogen limitation and microaerobic conditions on extended continuous cultivations of Saccharomyces cerevisiae with cell recirculation

Continuous fermentation of undetoxified dilute acid lignocellulose hydrolysate with Saccharomyces cerevisiae ATCC 96581 using cell recirculation

The fermentation performance of nine strains of Saccharomyces cerevisiae in batch and fed-batch cultures in dilute-acid wood hydrolysate

Effects of furfural on the respiratory metabolism of Saccharomyces cerevisiae in glucose-limited chemostats

Carbon starvation can induce energy deprivation and a loss of fermentative capacity in Saccharomyces cerevisiae.

Metabolic flux analysis of RQ-controlled microaerobic ethanol production by Saccharomyces cerevisiae

Metabolic flux analysis of RQ controlled microaerobic ethanol production by Saccharomyces cerevisiae,

Microaerobic glycerol formation in Saccharomyces cerevisiae

Growth and product formation in anaerobic and microaerobic continuous cultures of Saccharomyces cerevisiae under carbon- and nitrogen limitation.

Modeling the fluxes of reducing equivalents in microaerobic RQ-controlled continuous cultures of Saccharomyces cerevisiae.

Analysis and Control of Continuous Microaerobic Ethanol Production by Yeast

Use of the inlet gas composition to control the respiratory quotient in microaerobic bioprocesses.

A new method for studying microaerobic fermentation: I. A theoretical analysis of oxygen programmed fermentation.

Experimental Methods for Microaerobic Bioprocesses

Experimental methods for microaerobic bioprocesses : oxygen programmed fermentation and off-gas analysis by mass spectrometry

An experimental guide to the relevant aeration rates in microaerobic bioprocesses.

A new method for studying microaerobic fermentation: II. An experimental investigation of xylose fermentation.