John Fletcher

Visar 76 publikationer

2017

MS/MS analysis and imaging of lipids across Drosophila brain using secondary ion mass spectrometry

Nhu TN Phan, M. Munem, Andrew Ewing et al
Analytical and Bioanalytical Chemistry. Vol. 409 (16), p. 3923-3932
Artikel i vetenskaplig tidskrift
2016

Evaluation of biomolecular distributions in rat brain tissues by means of ToF-SIMS using a continuous beam of Ar clusters

Shusuke Nakano, Yuta Yokoyama, Satoka Aoyagi et al
Biointerphases. Vol. 11 (2), p. 02A307-1 - 5-
Artikel i vetenskaplig tidskrift
2016

Peptide Fragmentation and Surface Structural Analysis by Means of ToF-SIMS Using Large Cluster Ion Sources

Y. Yokoyama, S. Aoyagi, M. Fujii et al
Analytical Chemistry. Vol. 88 (7), p. 3592-3597
Artikel i vetenskaplig tidskrift
2016

Multimodal Imaging of Chemically Fixed Cells in Preparation for NanoSIMS

Jelena Lovric, Per Malmberg, Bengt R Johansson et al
Analytical Chemistry. Vol. 88 (17), p. 8841-8848
Artikel i vetenskaplig tidskrift
2016

Intact lipid imaging of mouse brain samples: MALDI, nanoparticle-laser desorption ionization, and 40 keV argon cluster secondary ion mass spectrometry

Amir Saeid Mohammadi, Nhu TN Phan, John Fletcher et al
Analytical and Bioanalytical Chemistry. Vol. 408 (24), p. 6857-6868
Artikel i vetenskaplig tidskrift
2016

Cholesterol Alters the Dynamics of Release in Protein Independent Cell Models for Exocytosis

Neda Najafinobar, Lisa Mellander, Michael Kurczy et al
Scientific Reports. Vol. 6 (Article number: 33702)
Artikel i vetenskaplig tidskrift
2016

Investigating the Role of the Stringent Response in Lipid Modifications during the Stationary Phase in E. coli by Direct Analysis with Time-of-Flight-Secondary Ion Mass Spectrometry

Patrick M. Wehrli, Tina B. Angerer, Anne Farewell et al
Analytical Chemistry. Vol. 88 (17), p. 8680-8688
Artikel i vetenskaplig tidskrift
2016

Optimizing sample preparation for anatomical determination in the hippocampus of rodent brain by ToF-SIMS analysis

Tina B. Angerer, Amir Saeid Mohammadi, John Fletcher
Biointerphases. Vol. 11 (2), p. artikel nr 02A319-
Artikel i vetenskaplig tidskrift
2015

High energy gas cluster ions for organic and biological analysis by time-of-flight secondary ion mass spectrometry

Tina B. Angerer, Paul Blenkinsopp, John Fletcher
International Journal of Mass Spectrometry. Vol. 377, p. 591-598
Artikel i vetenskaplig tidskrift
2015

Improved Molecular Imaging in Rodent Brain with Time-of-Flight-Secondary Ion Mass Spectrometry Using Gas Cluster Ion Beams and Reactive Vapor Exposure

Tina B. Angerer, Masoumeh Dowlatshahi Pour, Per Malmberg et al
Analytical Chemistry. Vol. 87 (8), p. 4305-4313
Artikel i vetenskaplig tidskrift
2015

Lipid Structural Effects of Oral Administration of Methylphenidate in Drosophila Brain by Secondary Ion Mass Spectrometry Imaging

Nhu TN Phan, John Fletcher, Andrew Ewing
Analytical Chemistry. Vol. 87 (8), p. 4063-4071
Artikel i vetenskaplig tidskrift
2015

Latest applications of 3D ToF-SIMS bio-imaging

John Fletcher
Biointerphases. Vol. 10 (1)
Artikel i vetenskaplig tidskrift
2015

Significant Enhancement of Negative Secondary Ion Yields by Cluster Ion Bombardment Combined with Cesium Flooding

P. Philipp, Tina B. Angerer, Sanna Sämfors et al
Analytical Chemistry. Vol. 87 (19), p. 10025-10032
Artikel i vetenskaplig tidskrift
2015

Measuring Compositions in Organic Depth Profiling: Results from a VAMAS Interlaboratory Study

A. G. Shard, R. Havelund, S. J. Spencer et al
Journal of Physical Chemistry B. Vol. 119 (33), p. 10784-10797
Artikel i vetenskaplig tidskrift
2015

Comparing depth profiling of oxide scale on SOFC interconnect-materials using ToF-SIMS with Ga-69(+), Bi-3(+)/Cs+ and C-60(+)/C-60(2+) as primary and sputter ions

Josefin Hall, U. Bexell, John Fletcher et al
Materials at High Temperatures. Vol. 32 (1-2), p. 133-141
Artikel i vetenskaplig tidskrift
2015

3D imaging of biological specimen using MS

John Fletcher
Bioanalysis. Vol. 7 (20), p. 2657-2666
Artikel i vetenskaplig tidskrift
2014

Examination of fragment ions of polystyrene in TOF-SIMS spectra using MS/MS

T. Kawashima, T. Kurosawa, S. Aoyagi et al
Surface and Interface Analysis. Vol. 46, p. 92-95
Artikel i vetenskaplig tidskrift
2014

Maximising the potential for bacterial phenotyping using time‐of‐flight secondary ion mass spectrometry with multivariate analysis and Tandem Mass Spectrometry

Patrick M. Wehrli, Erika Lindberg, Tina B. Angerer et al
Surface and Interface Analysis. Vol. 46 (1), p. 173-176
Artikel i vetenskaplig tidskrift
2014

Prospect of increasing secondary ion yields in ToF-SIMS using water cluster primary ion beams

S. Sheraz, A. Barber, I. B. Razo et al
Surface and Interface Analysis. Vol. 46, p. 51-53
Artikel i vetenskaplig tidskrift
2014

ToF-SIMS imaging of lipids and lipid related compounds in Drosophila brain

Nhu TN Phan, John Fletcher, Peter Sjövall et al
Surface and Interface Analysis. Vol. 46 (S1), p. 123-126
Paper i proceeding
2014

Imaging Mass Spectrometry for Single-Cell Analysis

Nhu TN Phan, John Fletcher, Andrew Ewing
Kapitel i bok
2014

3D Imaging of TiO2 nanoparticle accumulation in tetrahymena pyriformis

Tina B. Angerer, John Fletcher
Surface and Interface Analysis. Vol. 46 (S1), p. 198-203
Artikel i vetenskaplig tidskrift
2014

Gold and silver nanoparticle-assisted laser desorption ionization mass spectrometry compatible with secondary ion mass spectrometry for lipid analysis

Amir Saeid Mohammadi, John Fletcher, Per Malmberg et al
Surface and Interface Analysis. Vol. 46 (S1), p. 379-382
Paper i proceeding
2014

Analysis of liposome model systems by time-of-flight secondary ion mass spectrometry

Jelena Lovric, Jacqueline Keighron, Tina B. Angerer et al
Surface and Interface Analysis. Vol. 46 (S1), p. 74-78
Paper i proceeding
2014

Spatiotemporal lipid profiling during early embryo development of Xenopus laevis using dynamic Time-of-Flight Secondary Ion Mass Spectrometry (ToF-SIMS) Imaging

Hua Tian, John Fletcher, Raphael Thuret et al
Journal of Lipid Research. Vol. Epub ahead of print
Artikel i vetenskaplig tidskrift
2013

Secondary Ion Mass Spectrometry: Characterizing Complex Samples in Two and Three Dimensions.

John Fletcher, John C Vickerman
Analytical Chemistry. Vol. 85 (2), p. 610-639
Reviewartikel
2013

Evaluating the challenges associated with time-of-fight secondary ion mass spectrometry for metabolomics using pure and mixed metabolites

John Fletcher, Helen L Kotze, Emily G. Armitage et al
Metabolomics. Vol. 9 (3), p. 535-544
Artikel i vetenskaplig tidskrift
2013

Enhancing Secondary Ion Yields in Time of Flight-Secondary Ion Mass Spectrometry Using Water Cluster Primary Beams

Sadia Sheraz, Andrew Barber, John Fletcher et al
Analytical Chemistry. Vol. 85 (12), p. 5654−5658-
Artikel i vetenskaplig tidskrift
2013

Time-of-flight SIMS as a novel approach to unlocking the hypoxic properties of cancer

Emily G Armitage, Helen L Kotze, John Fletcher et al
Surface and Interface Analysis. Vol. 45 (1), p. 282-285
Artikel i vetenskaplig tidskrift
2013

Cluster and polyatomic primary ion beams

John Fletcher, Christopher Szakal
ToF-SIMS: Materials Analysis by Mass Spectrometry, 2nd Ed., p. 291-310
Kapitel i bok
2013

Time-of-Flight Secondary Ion Mass Spectrometry Based Molecular Histology of Human Spinal Cord Tissue and Motor Neurons

Jörg Hanrieder, Per Malmberg, Olle R Lindberg et al
Analytical Chemistry. Vol. 85 (18), p. 8741-8748
Artikel i vetenskaplig tidskrift
2013

Peptide structural analysis using continuous Ar cluster and C60 ion beams

Satoka Aoyagi, John Fletcher, Sadia Sheraz et al
Analytical and Bioanalytical Chemistry. Vol. 405 (21), p. 6621-6628
Artikel i vetenskaplig tidskrift
2013

Comparison of C60 and GCIB primary ion beams for the analysis of cancer cells and tumour sections

John Fletcher, Sadia Rabbani, Andrew M. Barber et al
Surface and Interface Analysis. Vol. 45 (1), p. 273-276
Artikel i vetenskaplig tidskrift
2013

ToF-SIMS as a tool for metabolic profiling small biomolecules in cancer systems

Helen L. Kotze, Emily G. Armitage, John Fletcher et al
Surface and Interface Analysis. Vol. 45 (1), p. 277-281
Artikel i vetenskaplig tidskrift
2013

Compositional characterisation of metallurgical grade silicon and porous silicon nanosponge particles

Edward G. Chadwick, N. V. V. Mogili, Colm O'Dwyer et al
RSC Advances. Vol. 3 (42), p. 19393-19402
Artikel i vetenskaplig tidskrift
2013

Peak picking as a pre-processing technique for imaging time of flight secondary ion mass spectrometry

Jimmy D. Moore, Alex Henderson, John Fletcher et al
Surface and Interface Analysis. Vol. 45 (1), p. 461-465
Artikel i vetenskaplig tidskrift
2013

The inherent problem of transflection-mode infrared spectroscopic microscopy and the ramifications for biomedical single point and imaging applications.

Paul Bassan, Joe Lee, Ashwin Sachdeva et al
The Analyst. Vol. 138 (1), p. 144-57
Artikel i vetenskaplig tidskrift
2012

A Comparative Study of Secondary Ion Emission from Water Ice under Ion Bombardment by Au(+), Au(3)(+), and C(60)(+)

Xavier A Conlan, John Fletcher, Nicholas P Lockyer et al
Journal of Physical Chemistry C. Vol. 114 (12), p. 5468-5479
Artikel i vetenskaplig tidskrift
2011

Molecular SIMS imaging; spatial resolution and molecular sensitivity: Have we reached the end of the road? Is there light at the end of the tunnel?

John Fletcher, Nicholas P. Lockyer, John C. Vickerman
Surface and Interface Analysis. Vol. 43 (1-2), p. 253-256
Paper i proceeding
2011

TOF-SIMS with Argon Gas Cluster Ion Beams: A Comparison with C(60)(+)

Sadia Rabbani, Andrew M. Barber, John Fletcher et al
Analytical Chemistry. Vol. 83 (10), p. 3793-3800
Artikel i vetenskaplig tidskrift
2011

A new time-of-flight SIMS instrument for 3D imaging and analysis

Rowland Hill, Paul Blenkinsopp, Stephen Thompson et al
Surface and Interface Analysis. Vol. 43 (1-2), p. 506-509
Paper i proceeding
2011

DEVELOPMENTS IN MOLECULAR SIMS DEPTH PROFILING AND 3D IMAGING OF BIOLOGICAL SYSTEMS USING POLYATOMIC PRIMARY IONS

John Fletcher, Nicholas P. Lockyer, John C. Vickerman
Mass Spectrometry Reviews. Vol. 30 (1), p. 142-174
Reviewartikel
2011

Label free biochemical 2D and 3D imaging using secondary ion mass spectrometry.

John Fletcher, John C Vickerman, Nicholas Winograd
Current opinion in chemical biology. Vol. 15 (5), p. 733-40
Reviewartikel
2011

Investigating the effect of temperature on depth profiles of biological material using ToF‐SIMS

Alan M. Piwowar, John Fletcher, Nicholas Lockyer et al
Surface and Interface Analysis. Vol. 43 (1-2), p. 207-210
Artikel i vetenskaplig tidskrift
2011

Top-down approach to studying biological components using ToF-SIMS

Alan M. Piwowar, John Fletcher, Nicholas P. Lockyer et al
Surface and Interface Analysis. Vol. 43 (1-2), p. 265-268
Artikel i vetenskaplig tidskrift
2011

Exploring subcellular imaging on the buncher-ToF J105 3D chemical imager

S. Rabbani, John Fletcher, N. P. Lockyer et al
Surface and Interface Analysis. Vol. 43 (1-2), p. 380-384
Paper i proceeding
2011

Three-dimensional mass spectral imaging of HeLa-M cells - sample preparation, data interpretation and visualisation

John Fletcher, Sadia Rabbani, Alex Henderson et al
Rapid Communications in Mass Spectrometry. Vol. 25 (7), p. 925-932
Artikel i vetenskaplig tidskrift
2010

Effects of Cryogenic Sample Analysis on Molecular Depth Profiles with TOF-Secondary Ion Mass Spectrometry

Alan M. Piwowar, John Fletcher, Jeanette Kordys et al
Analytical Chemistry. Vol. 82 (19), p. 8291-8299
Artikel i vetenskaplig tidskrift
2010

A new SIMS paradigm for 2D and 3D molecular imaging of bio-systems

John Fletcher, John C. Vickerman
Analytical and Bioanalytical Chemistry. Vol. 396 (1), p. 85-104
Reviewartikel
2010

2 and 3D TOF-SIMS Imaging for Biological Analysis

John Fletcher
Detection of Biological Agents For the Prevention of Bioterrorism, p. 285-299
Kapitel i bok
2010

Time of Flight Mass Spectrometry Imaging of Samples Fractured In Situ with a Spring-Loaded Trap System.

Ingela Lanekoff, Michael Kurczy, Rowland Hill et al
Analytical Chemistry. Vol. 82 (15), p. 6652-6659
Artikel i vetenskaplig tidskrift
2009

Explanatory multivariate analysis of ToF-SIMS spectra for the discrimination of bacterial isolates

Seetharaman Vaidyanathan, John Fletcher, Roger M. Jarvis et al
The Analyst. Vol. 134 (11), p. 2352-2360
Artikel i vetenskaplig tidskrift
2009

Cellular imaging with secondary ion mass spectrometry

John Fletcher
Analyst. Vol. 134 (11), p. 2204-2215
Reviewartikel
2009

A comparison of PCA and MAF for ToF-SIMS image interpretation

Alex Henderson, John Fletcher, John C. Vickerman
Surface and Interface Analysis. Vol. 41 (8), p. 666-674
Artikel i vetenskaplig tidskrift
2009

A Comparative Study of Secondary Ion Emission from Water Ice under Ion Bombardment by Au+, Au3+, and C60+

Conlan Xavier, John Fletcher, Nicholas P. Lockyer et al
Journal of Physical Chemistry C. Vol. 114 (12), p. 5468-5479
Artikel i vetenskaplig tidskrift
2008

Uncovering new challenges in bio-analysis with ToF-SIMS

John Fletcher, Alex Henderson, Gregory X. Biddulph et al
Applied Surface Science. Vol. 255 (4), p. 1264-1270
Paper i proceeding
2008

Exploratory analysis of TOF-SIMS data from biological surfaces

Seetharaman Vaidyanathan, John Fletcher, Alex Henderson et al
Applied Surface Science. Vol. 255 (4), p. 1599-1602
Paper i proceeding
2008

A New Dynamic in Mass Spectral Imaging of Single Biological Cells

John Fletcher, Sadia Rabbani, Alex Henderson et al
Analytical Chemistry. Vol. 80 (23), p. 9058-9064
Artikel i vetenskaplig tidskrift
2008

Subsurface Biomolecular Imaging of Streptomyces coelicolor Using Secondary Ion Mass Spectrometry

Seetharaman Vaidyanathan, John Fletcher, Roy Goodacre et al
Analytical Chemistry. Vol. 80 (6), p. 1942-1951
Artikel i vetenskaplig tidskrift
2008

TOF-SIMS investigation of Streptomyces coelicolor, a mycelial bacterium

Seetharaman Vaidyanathan, John Fletcher, Nicholas P. Lockyer et al
Applied Surface Science. Vol. 288 (4), p. 922-925
Artikel i vetenskaplig tidskrift
2008

Substrate effects on the analysis of biomolecular layers using Au+, Au3+ and C60+ bombardments

Jeanette Kordys, John Fletcher, Nicholas P. Lockyer et al
Applied Surface Science. Vol. 255 (4), p. 890-892
Artikel i vetenskaplig tidskrift
2007

TOF-SIMS 3D biomolecular imaging of Xenopus laevis oocytes using buckminsterfullerene (C-60) primary ions

John Fletcher, Nicholas P. Lockyer, Seetharaman Vaidyanathan et al
Analytical Chemistry. Vol. 79 (6), p. 2199-2206
Artikel i vetenskaplig tidskrift
2007

Properties of C-84 and C24H12 molecular ion sources for routine TOF-SIMS analysis

Gregory X. Biddulph, Alan M. Piwowar, John Fletcher et al
Analytical Chemistry. Vol. 79 (19), p. 7259-7266
Artikel i vetenskaplig tidskrift
2006

Molecular depth profiling of organic and biological materials

John Fletcher, Xavier A. Conlan, Nicholas P. Lockyer et al
Applied Surface Science. Vol. 252 (19), p. 6513-6516
Paper i proceeding
2006

C-60, buckminsterfullerene: its impact on biological ToF-SIMS analysis

John Fletcher, Nicholas P. Lockyer, John C. Vickerman
Surface and Interface Analysis. Vol. 38 (11), p. 1393-1400
Reviewartikel
2006

TOF-SIMS analysis using C-60- effect of impact energy on yield and damage

John Fletcher, X. A. Conlan, E. A. Jones et al
Analytical Chemistry. Vol. 78 (6), p. 1827-1831
Artikel i vetenskaplig tidskrift
2006

ToF-SIMS studies of Bacillus using multivariate analysis with possible identification and taxonomic applications

Charlotte E. Thompson, Joanne Ellis, John Fletcher et al
Applied Surface Science. Vol. 252 (19), p. 6719-6722
Artikel i vetenskaplig tidskrift
2006

Rapid discrimination of the causal agents of urinary tract infection using ToF-SIMS with chemometric cluster analysis

John Fletcher, A. Henderson, R. M. Jarvis et al
Applied Surface Science. Vol. 252 (19), p. 6869-6874
Paper i proceeding
2006

ToF-SIMS studies of Bacillus using multivariate analysis with possible identification and taxonomic applications

C. E. Thompson, J. Ellis, John Fletcher et al
Applied Surface Science. Vol. 252 (19), p. 6719-6722
Paper i proceeding
2006

ToF-SIMS analysis of bio-systems: Are polyatomic primary ions the solution?

E. A. Jones, John Fletcher, C. E. Thompson et al
Applied Surface Science. Vol. 252 (19), p. 6844-6854
Paper i proceeding
2006

A comparative study of secondary ion yield from model biological membranes using Au-n(+) and C-60(+) primary ion sources

M. J. Baker, John Fletcher, H. Jungnickel et al
Applied Surface Science. Vol. 252 (19), p. 6731-6733
Paper i proceeding
2004

ToF-SIMS Studies of Sulfuric Acid Hydrate Films

John Fletcher, Alex Henderson, Andrew B. Horn et al
Journal of Physical Chemistry B. Vol. 108 (19), p. 5960-5966
Artikel i vetenskaplig tidskrift
2004

ToF-SIMS analysis of atmospherically relevant sulphuric acid hydrate films and reactions thereof

John Fletcher, John C. Vickerman
Applied Surface Science. Vol. 231-232, p. 524-527
Artikel i vetenskaplig tidskrift
2003

The role of surface molecular hydrates in the heterogeneous interaction of NH3 with sulfuric acid monohydrate

KL Nash, RM Sayer, SB Couling et al
Physical Chemistry Chemical Physics. Vol. 5 (22), p. 5101-5107
Artikel i vetenskaplig tidskrift
2003

Identification of surface molecular hydrates on solid sulfuric acid films

SB Couling, KL Nash, John Fletcher et al
Journal of the American Chemical Society. Vol. 125 (43), p. 13038-13039
Artikel i vetenskaplig tidskrift
2003

First detection of molecular hydrate complexes in sulfuric acid aerosols

SB Couling, John Fletcher, AB Horn et al
Physical Chemistry Chemical Physics. Vol. 5 (19), p. 4108-4113
Artikel i vetenskaplig tidskrift

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