Johan Larsbrink

Genomic mining of <i>Geobacillus stearothermophilus</i> GF16 for xylose production from hemicellulose-rich biomasses using secreted enzymes

2024

Polysaccharide utilization loci from Bacteroidota encode CE15 enzymes with possible roles in cleaving pectin-lignin bonds

2024

Analyses of long-term fungal degradation of spruce bark reveals varying potential for catabolism of polysaccharides and extractive compounds

2024

A unique metabolic gene cluster regulates lactose and galactose metabolism in the yeast Candida intermedia

2024

Exploration of three Dyadobacter fermentans enzymes uncovers molecular activity determinants in CE15

Structure-based clustering and mutagenesis of bacterial tannases reveals the importance and diversity of active site-capping domains

2024

Structural and biochemical analysis of family 92 carbohydrate-binding modules uncovers multivalent binding to β-glucans

Boosting Enzyme Activity in Biomass Conversion by Modulating the Hydrolysis Process of Cellobiohydrolases

2024

Genomic mining of Geobacillus stearothermophilus GF16 for xylose production from hemicellulose-rich biomasses using secreted enzymes

Streptomyces castrisilvae sp. nov. and Streptomyces glycanivorans sp. nov., novel soil streptomycetes metabolizing mutan and alternan

Proteomic identification of putative enzymes for dental plaque deconstruction

Regulation of lactose and galactose growth: Insights from a unique metabolic gene cluster in Candida intermedia

Filamentous fungi display different behavior during spruce bark degradation.

2023

Enzymatic debranching is a key determinant of the xylan-degrading activity of family AA9 lytic polysaccharide monooxygenases

2023

Resin acids play key roles in shaping microbial communities during degradation of spruce bark

2023

Structural and functional investigation of a fungal member of carbohydrate esterase family 15 with potential specificity for rare xylans

2023

A unique AA5 alcohol oxidase fused with a catalytically inactive CE3 domain from the bacterium Burkholderia pseudomallei

2023

Glucuronoyl esterases - enzymes to decouple lignin and carbohydrates and enable better utilization of renewable plant biomass

Filamentous fungi display different behavior during spruce bark degradation.

2023

Yeasts Have Evolved Divergent Enzyme Strategies To Deconstruct and Metabolize Xylan

Characterization of three tannases from Clostridium butyricum active on oak bark extract

2022

Mechanism of the glucuronoyl esterase OtCE15A: an alpha/beta hydrolase involved with biomass conversion

2022

Glycan processing in gut microbiomes

Substrate and mechanistic investigation of the tannases CbTan1 and 2 - serine hydrolases active on gallotannins

2022

Structural diversity and substrate preferences of three tannase enzymes encoded by the anaerobic bacterium Clostridium butyricum

2022

Recombinant Protein L: Production, Purification and Characterization of a Universal Binding Ligand

Enzymes targeting lignin-carbohydrate complexes

2022

Mechanism and biomass association of glucuronoyl esterase: an α/β hydrolase with potential in biomass conversion

Alpha vs. Gamma: substrate specificity of CE15 enzymes

2022

Investigation and Alteration of Organic Acid Synthesis Pathways in the Mammalian Gut Symbiont Bacteroides thetaiotaomicron

Deciphering key stages, compounds, and microorganisms during microbial degradation of spruce bark

2021

Performance of Regression Models as a Function of Experiment Noise

2021

Characterization of a novel multidomain CE15-GH8 enzyme encoded by a polysaccharide utilization locus in the human gut bacterium Bacteroides eggerthii

2021

Genomic and transcriptomic analysis of the thermophilic lignocellulose-degrading fungus Thielavia terrestris LPH172

2021

The coordinated action of glucuronoyl esterase and α-glucuronidase promotes the disassembly of lignin–carbohydrate complexes

2021

Structure of a C1/C4-oxidizing AA9 lytic polysaccharide monooxygenase from the thermophilic fungus Malbranchea cinnamomea

2021

A polysaccharide utilization locus from the gut bacterium dysgonomonas mossii encodes functionally distinct carbohydrate esterases

Biochemical characterization of three tannases from Clostridium butyricum

2021

Polysaccharide degradation by the Bacteroidetes: mechanisms and nomenclature

2021

CAZyme prediction in ascomycetous yeast genomes guides discovery of novel xylanolytic species with diverse capacities for hemicellulose hydrolysis

2021

Phylogenetic analysis and in-depth characterization of functionally and structurally diverse CE5 cutinases

2021

Structural and Functional Analysis of a Multimodular Hyperthermostable Xylanase-Glucuronoyl Esterase from Caldicellulosiruptor kristjansonii

Bacteroidetes bacteria in the soil: Glycan acquisition, enzyme secretion, and gliding motility

2020

Structural insights of the enzymes from the chitin utilization locus of Flavobacterium johnsoniae

2020

Multimodular fused acetyl–feruloyl esterases from soil and gut Bacteroidetes improve xylanase depolymerization of recalcitrant biomass

2020

Investigation of a thermostable multi-domain xylanase-glucuronoyl esterase enzyme from Caldicellulosiruptor kristjanssonii incorporating multiple carbohydrate-binding modules

2019

Structural and biochemical studies of the glucuronoyl esterase OtCE15A illuminate its interaction with lignocellulosic components

Mapping the enzyme machineries of cellulolytic soil-dwelling Bacteroidetes

ACTIVE SITE EVOLUTION IN BIOMASS DEGRADING ENZYMES

Mapping the Enzyme Machineries of Cellulolytic Soil-Dwelling Bacteroidetes

Enzyme discovery and structure-function investigation of carbohydrate-active enzymes

2019

Surveying of acid-tolerant thermophilic lignocellulolytic fungi in Vietnam reveals surprisingly high genetic diversity

2019

Specific xylan activity revealed for AA9 Lytic Polysaccharide Monooxygenases of the thermophilic fungus Malbranchea cinnamomea by functional characterization

2019

Structure-function analyses reveal that a glucuronoyl esterase from Teredinibacter turnerae interacts with carbohydrates and aromatic compounds

Novel AA9 LPMOs from the thermophilic fungus Thielavia terrestris LPH 172

Understanding enzyme-substrate interactions in Carbohydrate Esterase Family 15

2018

Biochemical and structural features of diverse bacterial glucuronoyl esterases facilitating recalcitrant biomass conversion

2018

Genome sequence of Rhizomucor pusillus FCH 5.7, a thermophilic zygomycete involved in plant biomass degradation harbouring putative GH9 endoglucanases

2018

Mannanase hydrolysis of spruce galactoglucomannan focusing on the influence of acetylation on enzymatic mannan degradation

Proteomic Insights into the Cellulose Degradation Systems of Cytophaga hutchinsonii and Sporocytophaga myxococcoides

2018

Proteomic Dissection of the Cellulolytic Machineries Used by Soil-Dwelling Bacteroidetes

Biochemical and structural investigation of the CE15 family: Glucuronoyl esterases acting on recalcitrant biomass

Biochemical and structural diversity in Carbohydrate Esterase Family 15

Proteomic insights into mannan degradation and protein secretion by the forest floor bacterium Chitinophaga pinensis

2017

Proteomic data on enzyme secretion and activity in the bacterium Chitinophaga pinensis

2017

Combined genome and transcriptome sequencing to investigate the plant cell wall degrading enzyme system in the thermophilic fungus Malbranchea cinnamomea

The function of AA9 proteins in the thermophilic fungus Malbranchea cinnamomea

Structural dissection of a complex Bacteroides ovatus gene locus conferring xyloglucan metabolism in the human gut.

2016

A polysaccharide utilization locus from Flavobacterium johnsoniae enables conversion of recalcitrant chitin