Pernilla Wittung Stafshede
Pernilla Wittung-Stafshede är sedan 2015 professor (och avdelningschef 2015-2018) vid divisionen Kemisk Biologi vid institutionen Biologi och Bioteknik. Hon leder en forskargrupp som fokuserar på metallproteiner (t ex vid cancer) och felveckning (t ex vid Parksinon sjukdom). Pernilla har tidigare arbetat som professor i USA i 12 år vid universiteten Tulane (New Orleans) och Rice (Houston), samt, de följande 7 åren, vid Umeå Universitet innan hon kom till Chalmers. Pernilla Wittung-Stafshede har publicerat mer än 220 forskningsartiklar (2019) och många populärvetenskapliga texter. Sedan januari 2019 leder Pernilla Genie, Gender Initiative for Excellence, vilket är en 10-årig Stiftelse satsning som ska förbättra jämställdheten bland Chalmers lärare och forskare.
Wittung-Stafshede Forskningsgrupp
Genie
Genie (Insidan)

Visar 97 publikationer
Evaluation of copper chaperone ATOX1 as prognostic biomarker in breast cancer
My journey in academia: Things not on the CV
A gut bacterial amyloid promotes α-synuclein aggregation and motor impairment in mice
Role of Zero-Order Loop in Protein Unfolding Case Study with Apoazurin
Female Faculty: Why So Few and Why Care?
Redox-Dependent Copper Ion Modulation of Amyloid-β (1-42) Aggregation In Vitro
Mirror-Image 5S Ribonucleoprotein Complexes
Copper relay path through the N-terminus of Wilson disease protein, ATP7B
Alpha-Synuclein Binds to DNA and Modulates its Physical Properties
Wilson disease missense mutations in ATP7B affect metal-binding domain structural dynamics
Copper Chaperone Atox1 Interacts with Cell Cycle Proteins
Folding of copper proteins: Role of the metal?
Abundant fish protein inhibits α-synuclein amyloid formation
Copper chaperone blocks amyloid formation via ternary complex
Fucosylated Molecules Competitively Interfere with Cholera Toxin Binding to Host Cells
Alpha-Synuclein Modulates the Physical Properties of DNA
Geometrical Description of Protein Structural Motifs
In vitro analysis of α-synuclein amyloid formation and cross-reactivity
Synergistic effects of copper sites on apparent stability of multicopper oxidase, Fet3p
3D-Models of Insulin-Producing β-Cells: from Primary Islet Cells to Stem Cell-Derived Islets
A Luminal Loop of Wilson Disease Protein Binds Copper and Is Required for Protein Activity
Effects of small-molecule amyloid modulators on a Drosophila model of Parkinson's disease
Copper chaperone Atox1 plays role in breast cancer cell migration
Roles of copper-binding proteins in breast cancer
Defining the human copper proteome and analysis of its expression variation in cancers.
Probing functional roles of Wilson disease protein (ATP7B) copper-binding domains in yeast
A stretched conformation of DNA with a biological role?
Copper chaperone ATOX1 regulates pluripotency factor OCT4 in preimplantation mouse embryos
Gut Microbiota Regulate Motor Deficits and Neuroinflammation in a Model of Parkinson's Disease.
Extended functional repertoire for human copper chaperones
A Copper Story: From Protein Folding and Metal Transport to Cancer
Akademin is Sverige är ej så jämställd som du tror.
Attenuating Listeria monocytogenes Virulence by Targeting the Regulatory Protein PrfA
Protein Interactions that Enable Safe and Efficient Copper Ion Transport in the Human Cytoplasm
Cross-talk between amyloidogenic proteins in type-2 diabetes and Parkinson's disease
The C-Terminus of Human Copper Importer Ctr1 Acts as a Binding Site and Transfers Copper to Atox1
Is the gender gap solved in liberal Sweden?
Copper binding triggers compaction in N-terminal tail of human copper pump ATP7B
Enthalpy-entropy compensation at play in human copper ion transfer.
The bacterial curli system possesses a potent and selective inhibitor of amyloid formation.
Insulin-degrading enzyme prevents α-synuclein fibril formation in a nonproteolytical manner.
Human Copper Chaperone Atox1 Translocates to the Nucleus but does not Bind DNA In Vitro.
Human cytoplasmic copper chaperones Atox1 and CCS exchange copper ions in vitro.
Unresolved questions in human copper pump mechanisms.
Direct Correlation Between Ligand-Induced α-Synuclein Oligomers and Amyloid-like Fibril Growth.
Insulin-degrading enzyme is activated by the C-terminus of α-synuclein.
Cisplatin binds human copper chaperone Atox1 and promotes unfolding in vitro.
Recognition of Double-Stranded DNA by Peptide Nucleic Acids
Observation of a PNA-PNA-PNA triplex
Thermochemical and kinetic evidence for nucleotide-sequence-dependent RecA-DNA interactions
Peptide nucleic acids with a conformationally constrained chiral cyclohexyl-derived backbone
Ionic effects on the stability and conformation of peptide nucleic acid complexes
Second-site RecA - DNA interactions: Lack of identical recognition
Intelligent Nucleic Acid Interactions with Peptide Nucleic Acid (PNA) and Recombination Enzyme RecA
Direct observation of strand invasion by peptide nucleic acid (PNA) into double-stranded DNA
Functional interactions of nucleic acids : in simple DNA analogs and recombinase intermediates
Secondary Structure of RecA in Solution - The Effects of Cofactor, DNA and Ionic Conditions
Fluorescence-detected interactions of oligonucleotides in RecA complexes
Induced Chirality in PNA-PNA Duplexes
Phospholipid membrane permeability of peptide nucleic acid
INTERACTIONS OF DNA-BINDING LIGANDS WITH PNA DNA HYBRIDS
INTERACTIONS BETWEEN DNA-MOLECULES BOUND TO RECA FILAMENT - EFFECTS OF BASE COMPLEMENTARITY
DNA-LIKE DOUBLE HELIX FORMED BY PEPTIDE NUCLEIC-ACID
STRUCTURE-ACTIVITY STUDIES OF THE BINDING OF MODIFIED PEPTIDE NUCLEIC-ACIDS (PNAS) TO DNA
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Visar 11 forskningsprojekt
Strukturbestämning av Membranproteiner med Atomsondstomografi
Hjälp en forskare - subprojekt 2020 Stjärnjakten
Mekanismer för kopparproteinet Atox1 vid sjukdom
Kopparjoners roll vid spridning av cancer
Combining nonlinear spectroscopy and stem cells to understand our "fat problem"
Molekylära samspel mellan metalljoner och proteiner vid Parkinsons sjukdom
Spegelvänd bioteknik med spegelvända enzymer
Mekanismer för kopparjontransport i mänskliga celler
Early structural transformations that promote Parkinson's disease
Female Investigators in Nonlinear Optical Nanoscopy - FINON (FINON)