Pernilla Wittung Stafshede
Pernilla Wittung-Stafshede är sedan 2015 professor (och avdelningschef 2015-2018) vid divisionen Kemisk Biologi vid institutionen Biologi och Bioteknik. Hon leder en forskargrupp som fokuserar på metallproteiner (t ex vid cancer) och felveckning (t ex vid Parksinon sjukdom). Pernilla har tidigare arbetat som professor i USA i 12 år vid universiteten Tulane (New Orleans) och Rice (Houston), samt, de följande 7 åren, vid Umeå Universitet innan hon kom till Chalmers. Pernilla Wittung-Stafshede har publicerat mer än 260 forskningsartiklar (2022) och många populärvetenskapliga texter. Sedan januari 2019 leder Pernilla Genie, Gender Initiative for Excellence, vilket är en 10-årig Stiftelse satsning som ska förbättra jämställdheten bland Chalmers lärare och forskare.
Visar 122 publikationer
Distinct growth regimes of α-synuclein amyloid elongation
Chemical catalysis by biological amyloids
Memo1 reduces copper-mediated reactive oxygen species in breast cancer cells
Amyloids of α-Synuclein Promote Chemical Transformations of Neuronal Cell Metabolites
Amyloid Fibers of α-Synuclein Catalyze Chemical Reactions
Crossroads between copper ions and amyloid formation in Parkinson's disease
Frustration Dynamics and Electron-Transfer Reorganization Energies in Wild-Type and Mutant Azurins
Response to crowded conditions reveals compact nucleus for amyloid formation of folded protein
Another pearl in the “copper-transport” necklace
C-terminal truncation of α-synuclein alters DNA structure from extension to compaction
Macromolecular crowding modulates α-synuclein amyloid fiber growth
Atp7a-regulated enzyme metalation and trafficking in the menkes disease puzzle
The copper chaperone CCS facilitates copper binding to MEK1/2 to promote kinase activation
Impact of crowded environments on binding between protein and single-stranded DNA
Effects of the toxic metals arsenite and cadmium on α-synuclein aggregation in vitro and in cells
Ska vi verkligen ge Astra Zenecas vaccin till äldre?
The Zero-Order Loop in Apoazurin Modulates Folding Mechanism In Silico
A gut bacterial amyloid promotes α-synuclein aggregation and motor impairment in mice
Role of Zero-Order Loop in Protein Unfolding Case Study with Apoazurin
My journey in academia: Things not on the CV
Female Faculty: Why So Few and Why Care?
Redox-Dependent Copper Ion Modulation of Amyloid-β (1-42) Aggregation In Vitro
Mirror-Image 5S Ribonucleoprotein Complexes
Evaluation of copper chaperone ATOX1 as prognostic biomarker in breast cancer
Wilson disease missense mutations in ATP7B affect metal-binding domain structural dynamics
Alpha-Synuclein Binds to DNA and Modulates its Physical Properties
Copper relay path through the N-terminus of Wilson disease protein, ATP7B
Alpha-Synuclein Modulates the Physical Properties of DNA
Folding of copper proteins: Role of the metal?
Geometrical Description of Protein Structural Motifs
Abundant fish protein inhibits α-synuclein amyloid formation
Fucosylated Molecules Competitively Interfere with Cholera Toxin Binding to Host Cells
Copper Chaperone Atox1 Interacts with Cell Cycle Proteins
3D-Models of Insulin-Producing β-Cells: from Primary Islet Cells to Stem Cell-Derived Islets
In vitro analysis of α-synuclein amyloid formation and cross-reactivity
Synergistic effects of copper sites on apparent stability of multicopper oxidase, Fet3p
Copper chaperone blocks amyloid formation via ternary complex
A Luminal Loop of Wilson Disease Protein Binds Copper and Is Required for Protein Activity
Copper chaperone ATOX1 regulates pluripotency factor OCT4 in preimplantation mouse embryos
Roles of copper-binding proteins in breast cancer
Defining the human copper proteome and analysis of its expression variation in cancers.
Effects of small-molecule amyloid modulators on a Drosophila model of Parkinson's disease
Copper chaperone Atox1 plays role in breast cancer cell migration
A stretched conformation of DNA with a biological role?
Probing functional roles of Wilson disease protein (ATP7B) copper-binding domains in yeast
The C-Terminus of Human Copper Importer Ctr1 Acts as a Binding Site and Transfers Copper to Atox1
A Copper Story: From Protein Folding and Metal Transport to Cancer
Copper binding triggers compaction in N-terminal tail of human copper pump ATP7B
Protein Interactions that Enable Safe and Efficient Copper Ion Transport in the Human Cytoplasm
Attenuating Listeria monocytogenes Virulence by Targeting the Regulatory Protein PrfA
Gut Microbiota Regulate Motor Deficits and Neuroinflammation in a Model of Parkinson's Disease.
Is the gender gap solved in liberal Sweden?
Akademin is Sverige är ej så jämställd som du tror.
Cross-talk between amyloidogenic proteins in type-2 diabetes and Parkinson's disease
Extended functional repertoire for human copper chaperones
Enthalpy-entropy compensation at play in human copper ion transfer.
Direct Correlation Between Ligand-Induced α-Synuclein Oligomers and Amyloid-like Fibril Growth.
The bacterial curli system possesses a potent and selective inhibitor of amyloid formation
Unresolved questions in human copper pump mechanisms.
Human cytoplasmic copper chaperones Atox1 and CCS exchange copper ions in vitro.
Human Copper Chaperone Atox1 Translocates to the Nucleus but does not Bind DNA In Vitro.
Insulin-degrading enzyme is activated by the C-terminus of α-synuclein.
Insulin-degrading enzyme prevents α-synuclein fibril formation in a nonproteolytical manner.
Cisplatin binds human copper chaperone Atox1 and promotes unfolding in vitro.
Detection of point mutations in DNA by PNA-based quartz-crystal biosensor
In vitro membrane penetration of modified peptide nucleic acid (PNA)
Recognition of Double-Stranded DNA by Peptide Nucleic Acids
Observation of a PNA-PNA-PNA triplex
Peptide nucleic acids with a conformationally constrained chiral cyclohexyl-derived backbone
Thermochemical and kinetic evidence for nucleotide-sequence-dependent RecA-DNA interactions
Second-site RecA - DNA interactions: Lack of identical recognition
Direct observation of strand invasion by peptide nucleic acid (PNA) into double-stranded DNA
Ionic effects on the stability and conformation of peptide nucleic acid complexes
Intelligent Nucleic Acid Interactions with Peptide Nucleic Acid (PNA) and Recombination Enzyme RecA
Induced Chirality in PNA-PNA Duplexes
Phospholipid membrane permeability of peptide nucleic acid
Fluorescence-detected interactions of oligonucleotides in RecA complexes
Functional interactions of nucleic acids : in simple DNA analogs and recombinase intermediates
Secondary Structure of RecA in Solution - The Effects of Cofactor, DNA and Ionic Conditions
DNA-LIKE DOUBLE HELIX FORMED BY PEPTIDE NUCLEIC-ACID
INTERACTIONS OF DNA-BINDING LIGANDS WITH PNA DNA HYBRIDS
STRUCTURE-ACTIVITY STUDIES OF THE BINDING OF MODIFIED PEPTIDE NUCLEIC-ACIDS (PNAS) TO DNA
INTERACTIONS BETWEEN DNA-MOLECULES BOUND TO RECA FILAMENT - EFFECTS OF BASE COMPLEMENTARITY
Ladda ner publikationslistor
Du kan ladda ner denna lista till din dator.
Filtrera och ladda ner publikationslista
Som inloggad användare hittar du ytterligare funktioner i MyResearch.
Du kan även exportera direkt till Zotero eller Mendeley genom webbläsarplugins. Dessa hittar du här:
Zotero Connector
Mendeley Web Importer
Tjänsten SwePub erbjuder uttag av Researchs listor i andra format, till exempel kan du få uttag av publikationer enligt Harvard och Oxford i .RIS, BibTex och RefWorks-format.
Visar 15 forskningsprojekt
Katalytisk aktivitet hos amyloida fibrer
Role of Copper Binding to oncogenic Memo1 in Breast Cancer Cells
Role of copper chaperone Atox1 in breast cancer metastasis
Strukturbestämning av Membranproteiner med Atomsondstomografi
Hjälp en forskare - subprojekt 2020 Stjärnjakten
Mekanismer för kopparproteinet Atox1 vid sjukdom
Jämställdhet för excellens (Genie)
Kopparjoners roll vid spridning av cancer
Combining nonlinear spectroscopy and stem cells to understand our "fat problem"
Molekylära samspel mellan metalljoner och proteiner vid Parkinsons sjukdom
Spegelvänd bioteknik med spegelvända enzymer
Mekanismer för kopparjontransport i mänskliga celler
Early structural transformations that promote Parkinson's disease
Female Investigators in Nonlinear Optical Nanoscopy - FINON (FINON)